GNH USA

Europe — EMA

Levocetirizin Actavis

GNH USA supplies Levocetirizin Actavis (Levocetirizine), an antihistamine for allergic rhinitis and chronic idiopathic urticaria. Request a quote for supply.

Levocetirizine Dihydrochloride

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What is Levocetirizine Dihydrochloride?

Levocetirizine, the active ingredient in Levocetirizin Actavis, is an antihistamine presented as an oral tablet for systemic use. It reduces symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children as directed by a healthcare professional.

GNH USA supplies Levocetirizin Actavis as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide from its EU‑sourced manufacturing network. Our distribution ensures consistent quality and regulatory adherence across global markets.

What is Levocetirizine Dihydrochloride used for?

Levocetirizine is an antihistamine that targets histamine‑mediated allergic conditions.

Allergic rhinitis (seasonal or perennial): alleviates nasal congestion, sneezing, itching and rhinorrhea. Chronic idiopathic urticaria: decreases the frequency and severity of hives and associated itching. Allergic conjunctivitis: helps reduce eye itching and redness caused by histamine release.

What are the side effects of Levocetirizine Dihydrochloride?

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness or mild sedation - Fatigue or feeling of tiredness - Dry mouth - Headache - Nausea - Abdominal discomfort

Serious or Rare Side Effects: - Angioedema or swelling of the face, lips or tongue - Anaphylactic reactions - Severe skin reactions such as Stevens‑Johnson syndrome - Tachycardia or irregular heartbeat - Hepatic dysfunction - Blood dyscrasias including neutropenia or thrombocytopenia

What precautions apply to Levocetirizine Dihydrochloride?

Before initiating therapy, consider the following precautions.

Pregnancy: consult a healthcare provider to assess risk‑benefit. Breastfeeding: evaluate potential exposure to the infant. Renal impairment: dose adjustment may be required in reduced kidney function. Elderly patients: monitor for increased sedation or confusion. Drug interactions: review concomitant medications for possible additive effects. Store at ambient temperature: keep below 25 °C, retain in the original packaging, and protect from moisture.

What does Levocetirizine Dihydrochloride interact with?

Levocetirizine may interact with several medicines; categorize them as follows.

Major Interactions (Avoid): - Alcohol: can enhance sedation and drowsiness. - Central nervous system depressants (e.g., benzodiazepines, opioids): additive sedative effect. - Antifungal ketoconazole: may increase plasma concentrations of levocetirizine.

Moderate Interactions (Monitor Closely): - Ritonavir: potential increase in exposure. - Theophylline: possible reduction in clearance. - Macrolide antibiotics (e.g., erythromycin): may affect metabolism and plasma levels.

Frequently asked questions

What is Levocetirizin Actavis used for?+
Levocetirizin Actavis contains levocetirizine, an antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria. It helps reduce nasal congestion, sneezing, itching, and the formation of hives, providing symptomatic control in patients with these allergic conditions.
How does levocetirizine work?+
Levocetirizine selectively blocks peripheral histamine H1 receptors, preventing histamine released during allergic reactions from binding to these sites. This inhibition reduces vascular permeability, nerve stimulation, and smooth‑muscle contraction, thereby alleviating the typical signs of allergy such as itching, swelling, and nasal discharge.
What is the usual dose of Levocetirizin Actavis?+
The appropriate dose of Levocetirizin Actavis is determined by a qualified prescriber based on the patient’s age, clinical condition, renal function and other individual factors. Healthcare professionals tailor the regimen to achieve optimal symptom control while minimizing potential adverse effects.
Is Levocetirizin Actavis safe during pregnancy or breastfeeding?+
Safety data for levocetirizine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Pregnant or nursing women should discuss the medication with their healthcare provider before starting therapy.
How do I order Levocetirizin Actavis from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levocetirizin Actavis compare with other antihistamines?+
Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides more selective H1‑receptor blockade and fewer anticholinergic side effects, making it a preferred option for many patients requiring daily allergy control.
How should Levocetirizin Actavis be stored and handled?+
Store the tablets at ambient temperature, preferably below 25 °C, in their original blister pack or container. Protect them from moisture, direct sunlight and excessive heat. Keep the product out of reach of children and do not use it after the expiry date indicated on the packaging.
How is Levocetirizin Actavis given or administered?+
Levocetirizin Actavis is administered orally, typically as a tablet swallowed whole with water. It can be taken with or without food, according to the prescriber’s instructions. Patients should follow the dosing schedule provided by their healthcare professional and avoid crushing or chewing the tablet unless directed otherwise.
What are the most serious risks associated with Levocetirizin Actavis?+
While generally well tolerated, serious adverse events can include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, tachycardia, hepatic dysfunction and hematologic abnormalities. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, difficulty breathing, or unexplained fatigue.
Who should not use Levocetirizin Actavis?+
Levocetirizin Actavis should be avoided in individuals with known hypersensitivity to levocetirizine, other piperazine antihistamines, or any of the product’s excipients. Caution is also advised for patients with severe renal impairment, uncontrolled asthma, or those taking medications that may cause significant drug‑drug interactions without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levocetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Actavis Group Ptc Ehf.
Origin
EU

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