GNH USA

Europe — EMA

Levobupivacaina Kabi

GNH USA supplies Levobupivacaina Kabi (Levobupivacaine), a local anesthetic for epidural, spinal and peripheral nerve block.

Levobupivacaine Hydrochloride

Request sourcing

1
Pack/s

What is Levobupivacaine Hydrochloride?

Levobupivacaine Hydrochloride, the active ingredient in Levobupivacaina Kabi, is a local anesthetic (amide type) presented as a sterile solution for epidural, infiltration and intrathecal use. It provides reversible nerve block for surgical and diagnostic procedures in adult patients. GNH USA supplies Levobupivacaina Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levobupivacaine Hydrochloride used for?

Levobupivacaina Kabi is a local anesthetic used in regional anesthesia techniques. - Epidural anesthesia: produces analgesia for lower‑body surgeries and obstetric procedures. - Spinal (intrathecal) anesthesia: provides rapid, dense block for lower‑limb and pelvic operations. - Peripheral nerve block: enables targeted anesthesia of specific nerves for orthopedic or trauma surgery. - Infiltration anesthesia: allows local pain control for soft‑tissue procedures and postoperative analgesia.

What are the side effects of Levobupivacaine Hydrochloride?

Adverse reactions may occur following administration of Levobupivacaina Kabi.

Common Side Effects: - Hypotension: transient drop in blood pressure. - Bradycardia: slowed heart rate. - Dizziness or light‑headedness. - Nausea or vomiting. - Metallic taste in the mouth. - Headache.

Serious or Rare Side Effects: - Cardiac arrhythmia or cardiac arrest. - Seizures or central nervous system toxicity. - Respiratory depression or apnea. - Prolonged motor block. - Allergic reaction including rash or anaphylaxis. - Methemoglobinemia.

What precautions apply to Levobupivacaine Hydrochloride?

Prior to using Levobupivacaina Kabi, clinicians should consider several safety measures. - Assess cardiovascular status: monitor blood pressure and heart rate before and during administration. - Evaluate hepatic function: dose may need adjustment in severe liver disease. - Review patient medication list: avoid concurrent use with other potent local anesthetics. - Use incremental dosing: inject slowly and observe for signs of toxicity. - Store at ambient temperature: keep in the original container, protect from light and moisture.

What does Levobupivacaine Hydrochloride interact with?

Levobupivacaina Kabi can interact with other drugs that affect cardiac or central nervous system function.

Major Interactions (Avoid): - Class I antiarrhythmic agents (e.g., bupivacaine): additive cardiotoxicity. - Beta‑adrenergic blockers: may enhance bradycardia and hypotension. - Inhalational anesthetics (e.g., halothane): increase risk of neurotoxicity.

Moderate Interactions (Monitor Closely): - Opioids: may potentiate central nervous system depression. - Muscle relaxants: may increase neuromuscular blockade. - Diuretics: can exacerbate hypotension when combined.

Frequently asked questions

What is Levobupivacaina Kabi used for?+
Levobupivacaina Kabi is a sterile solution of levobupivacaine hydrochloride used to provide regional anesthesia. It is indicated for epidural, spinal (intrathecal), peripheral nerve block, and infiltration anesthesia, helping to achieve surgical analgesia and postoperative pain control.
How does levobupivacaine work?+
Levobupivacaine works by reversibly blocking voltage‑gated sodium channels on neuronal membranes. This prevents sodium influx needed for depolarisation, thereby inhibiting the initiation and propagation of nerve impulses and producing a reversible loss of sensation in the area where it is administered.
What is the usual dose of Levobupivacaina Kabi?+
The dose of Levobupivacaina Kabi is determined by the prescribing clinician based on the type of procedure, patient characteristics, and route of administration. The prescriber selects the appropriate concentration, volume and injection technique to achieve the desired anesthetic effect.
Is Levobupivacaina Kabi safe in pregnancy or breastfeeding?+
Safety data for levobupivacaine during pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Use during pregnancy or while breastfeeding should only occur if the potential benefit justifies the potential risk, and under close medical supervision.
How do I order Levobupivacaina Kabi from GNH USA?+
To order Levobupivacaina Kabi, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levobupivacaina Kabi compare with bupivacaine?+
Levobupivacaina Kabi contains levobupivacaine, the S‑enantiomer of bupivacaine, offering a similar duration of anesthesia with a lower risk of cardiotoxicity and central nervous system toxicity. Clinicians often prefer levobupivacaine when a safer cardiac profile is desired, especially in high‑risk patients.
What are the storage and handling requirements for Levobupivacaina Kabi?+
Levobupivacaina Kabi should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the solution from direct light, moisture and freezing. Inspect the vial for particulate matter before use and discard if the solution appears discoloured.
How is Levobupivacaina Kabi administered?+
Levobupivacaina Kabi is administered by a qualified healthcare professional via epidural, intrathecal (spinal) or peripheral nerve block techniques, or as an infiltration injection. The solution is injected slowly under aseptic conditions, with dosage and volume tailored to the specific procedure.
What are the most serious risks associated with Levobupivacaina Kabi?+
Serious risks include cardiac arrhythmias, cardiac arrest, seizures, severe respiratory depression, prolonged motor block, allergic reactions and methemoglobinemia. Prompt recognition of toxicity signs and immediate supportive measures are essential to mitigate these potentially life‑threatening events.
Who should not receive Levobupivacaina Kabi?+
Levobupivacaina Kabi should be avoided in patients with known hypersensitivity to levobupivacaine or other amide‑type local anesthetics, those with severe cardiac conduction disorders, uncontrolled epilepsy, or in situations where a safer alternative anesthetic is preferred. Clinical judgment is required for each case.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levobupivacaine Hydrochloride
Route
Epidural Use , Infiltration , Intrathecal Use , Pe
Manufacturer
Fresenius Kabi Italia S.R.L.
Origin
EU

Related products