Levitra

Vardenafil, the active ingredient in Levitra, is a phosphodiesterase type 5 inhibitor presented as an oral tablet for oral use. It treats erectile dysfunction in adult males by enhancing erectile response when sexual stimulation occurs.

GNH USA supplies Levitra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levitra belongs to the phosphodiesterase type 5 inhibitor class and is indicated for conditions affecting erectile function.

- Erectile dysfunction: improves the ability to achieve and maintain an erection sufficient for sexual activity when sexually stimulated.

Levitra may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Headache: mild to moderate pain in the head. - Flushing: warmth and redness of the face or upper body. - Dyspepsia: upset stomach or indigestion. - Nasal congestion: blocked or runny nose. - Back pain: discomfort in the lower back region. - Visual disturbances: blurred vision or changes in colour perception.

Serious or Rare Side Effects: - Priapism: prolonged erection lasting more than four hours. - Sudden vision loss: acute loss of vision in one or both eyes. - Sudden hearing loss: unexplained loss of hearing or ringing in the ears. - Cardiovascular events: chest pain, heart attack, or stroke in susceptible individuals. - Severe allergic reaction: rash, itching, swelling, or difficulty breathing. - Hypotension: marked drop in blood pressure causing dizziness or fainting.

Before prescribing Levitra, clinicians should evaluate patient history and comorbidities.

- Cardiovascular assessment: ensure the patient can tolerate sexual activity. - Nitrate therapy: avoid concurrent use with nitrates due to risk of severe hypotension. - Liver impairment: dose adjustment may be required in moderate to severe hepatic disease. - Renal impairment: consider dose reduction in patients with severe renal dysfunction. - Visual disorders: use caution in patients with retinal diseases such as retinitis pigmentosa. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Levitra can interact with several medication classes, requiring careful management.

Major Interactions (Avoid): - Nitrates (e.g., nitroglycerin, isosorbide dinitrate): may cause life‑threatening hypotension. - Guanylate cyclase stimulators (e.g., riociguat): additive vasodilatory effect leading to severe blood pressure drop. - Strong CYP3A4 inhibitors (e.g., ritonavir): can markedly increase Vardenafil plasma levels.

Moderate Interactions (Monitor Closely): - Moderate CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may increase exposure, requiring dose adjustment. - CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce effectiveness. - Alpha‑blockers (e.g., doxazosin, tamsulosin): may cause additive blood pressure lowering; monitor blood pressure.