GNH USA

Europe — EMA

Leviadex (Dexketoprofen)

GNH USA supplies Leviadex (Dexketoprofen), a nonsteroidal anti-inflammatory drug for mild to moderate acute pain, musculoskeletal pain and dysmenorrhea.

Dexketoprofen

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What is Dexketoprofen?

Dexketoprofen, the active ingredient in Leviadex, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for systemic use. It is indicated for mild to moderate acute pain, musculoskeletal pain, postoperative pain and dysmenorrhea in adult patients. GNH USA supplies Leviadex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dexketoprofen used for?

Leviadex (dexketoprofen) acts on inflammatory pathways to relieve pain in several clinical settings. - Mild to moderate acute pain: provides rapid analgesia for short‑term painful episodes. - Musculoskeletal pain: reduces discomfort associated with strains, sprains and arthritic conditions. - Post‑operative pain: helps control pain following surgical procedures. - Dysmenorrhea: alleviates menstrual‑related cramping and pelvic pain.

What are the side effects of Dexketoprofen?

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Dyspepsia: discomfort or burning in the upper abdomen. - Headache: transient cranial pain. - Dizziness: sensation of light‑headedness. - Abdominal pain: cramping or tenderness. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: potentially life‑threatening haemorrhage. - Renal impairment: reduced kidney function or acute failure. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Severe allergic reactions: anaphylaxis, angioedema, or skin rash. - Cardiovascular events: increased risk of myocardial infarction or stroke. - Stevens‑Johnson syndrome: rare but serious skin disorder.

What precautions apply to Dexketoprofen?

Before prescribing Leviadex, clinicians should consider several safety aspects. - Assess renal function: avoid use in severe renal impairment. - Evaluate gastrointestinal risk: use cautiously in patients with a history of ulcers or bleeding. - Review cardiovascular history: consider alternatives for patients with established heart disease. - Use the lowest effective dose: limit duration to the shortest period necessary. - Avoid concomitant NSAIDs: reduce risk of additive toxicity. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

What does Dexketoprofen interact with?

Dexketoprofen may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - Corticosteroids: synergistic ulcerogenic effect. - Selective serotonin reuptake inhibitors (SSRIs): elevated haemorrhage potential.

Moderate Interactions (Monitor Closely): - Antihypertensives (e.g., ACE inhibitors, ARBs): possible reduction in blood pressure control. - Diuretics: risk of renal function decline. - Lithium: potential increase in lithium serum levels. - Methotrexate: reduced clearance leading to toxicity.

Frequently asked questions

What is Leviadex used for?+
Leviadex contains dexketoprofen, an NSAID indicated for the relief of mild to moderate acute pain, musculoskeletal pain, postoperative pain and dysmenorrhea. It is prescribed for adult patients who need rapid analgesia in these clinical situations.
How does dexketoprofen work?+
Dexketoprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation and decrease the sensitisation of pain receptors, providing analgesic and anti‑inflammatory effects.
What is the usual dose of Leviadex?+
The specific dose and dosing schedule of Leviadex are determined by the prescribing healthcare professional based on the patient’s condition, severity of pain and individual risk factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Leviadex safe during pregnancy or breastfeeding?+
Safety data for dexketoprofen in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.
How do I order Leviadex from GNH USA?+
To request Leviadex, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Leviadex compare with other NSAIDs such as ibuprofen?+
Dexketoprofen is the active enantiomer of ketoprofen and generally provides faster onset of analgesia compared with many traditional NSAIDs like ibuprofen. Both share similar mechanisms and safety profiles, but individual tolerability and specific clinical scenarios may influence the choice of agent.
How should Leviadex be stored and handled?+
Leviadex should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.
How is Leviadex administered?+
Leviadex is taken orally, usually with a glass of water. It may be taken with or without food, but patients who experience gastrointestinal discomfort are advised to take it with meals to minimise irritation.
What are the most serious risks associated with Leviadex?+
Serious risks include gastrointestinal ulceration or bleeding, renal impairment, severe allergic reactions such as anaphylaxis, and rare cardiovascular events like myocardial infarction or stroke. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.
Who should not use Leviadex?+
Leviadex should be avoided in individuals with known hypersensitivity to dexketoprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and patients who are concurrently using other NSAIDs, anticoagulants or corticosteroids without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Dexketoprofen
Route
Oral Use
Manufacturer
Pharmacare Srl
Origin
EU

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