Europe — EMA
Зеквипра
Зеквипра (Letrozole) is an oral prescription aromatase inhibitor used primarily for hormone receptor-positive breast cancer in postmenopausal women. This non-st
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What is Letrozole?
Зеквипра (Letrozole) is an oral prescription aromatase inhibitor used primarily for hormone receptor-positive breast cancer in postmenopausal women. This non-steroidal medication works by lowering estrogen levels to slow tumor growth. It is also prescribed off-label for ovulation induction in fertility treatments. Always use as directed by a healthcare provider.
What is Letrozole used for?
Letrozole is primarily prescribed to treat early-stage hormone receptor-positive breast cancer in postmenopausal women. It is also used as adjuvant therapy after initial treatment to reduce recurrence risk. In fertility medicine, it may help stimulate ovulation in women with polycystic ovary syndrome or unexplained infertility. Some doctors prescribe it off-label for endometriosis-related pain or male infertility. It belongs to a class of medications that block estrogen production in peripheral tissues.
What are the side effects of Letrozole?
Letrozole is taken orally and may cause mild to moderate side effects such as hot flashes, joint pain, fatigue, or mild nausea. Some users report temporary muscle weakness or dizziness, especially when starting treatment. These effects are generally temporary and often improve over time. It may also affect cholesterol levels or bone density with long-term use. Always monitor your body’s response and report persistent symptoms to your doctor.
What precautions apply to Letrozole?
Keep this medication in its original packaging at room temperature away from moisture and heat. Store securely out of reach of children and pets. Do not use if the seal is broken or the product shows signs of tampering. Inform your healthcare provider about all current medications and medical conditions before starting letrozole. Use effective contraception during treatment if pregnancy is possible, as this drug may harm an unborn baby.
What does Letrozole interact with?
Letrozole may interact with other hormone therapies, tamoxifen, or estrogen-containing products, potentially reducing effectiveness. Alcohol and certain herbal supplements like black cohosh may increase side effects such as dizziness or liver stress. CYP2A6 inhibitors (e.g., some antifungals) could raise letrozole levels in the blood. Always review your full medication list with your doctor to avoid interactions.
Frequently asked questions
What is letrozole used for?+
How should letrozole be stored?+
Can letrozole cause side effects?+
Is letrozole safe during pregnancy?+
What should I avoid while taking letrozole?+
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