GNH USA

Europe — EMA

Letizen S

GNH USA supplies Letizen S (Cetirizine), a H1 receptor antagonist for allergic rhinitis and urticaria. Request a quote for hospitals and pharmacies.

Cetirizine Dihydrochloride

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1
Pack/s

What is Cetirizine Dihydrochloride?

Cetirizine, the active ingredient in Letizen S, is a H1 receptor antagonist presented as an oral tablet for oral use. It relieves symptoms of allergic rhinitis and urticaria in adults and children when appropriate. GNH USA supplies Letizen S as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Cetirizine Dihydrochloride used for?

Letizen S, an antihistamine, acts on the histamine H1 pathway to control allergic conditions. Allergic rhinitis: reduces nasal congestion, itching, sneezing and watery discharge. Urticaria: alleviates itching and hives associated with chronic or acute hives. Allergic conjunctivitis: helps diminish eye itching, redness and tearing.

What are the side effects of Cetirizine Dihydrochloride?

Common Side Effects: - Drowsiness: mild to moderate sleepiness. - Fatigue: feeling of reduced energy. - Dry mouth: decreased salivation. - Headache: mild cranial pain. - Nausea: upset stomach. - Dizziness: light‑headed sensation.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical care. - Stevens‑Johnson syndrome: rare skin disorder with blistering. - Angioedema: swelling of face, lips or tongue. - Hepatotoxicity: abnormal liver function tests.

What precautions apply to Cetirizine Dihydrochloride?

Before using Letizen S, consider the following precautions. Pregnancy: consult a healthcare professional before use. Breastfeeding: use with caution; discuss with a physician. Renal impairment: dose adjustment may be required. Concomitant CNS depressants: monitor for enhanced sedation. Alcohol: avoid or limit intake to reduce drowsiness. Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

What does Cetirizine Dihydrochloride interact with?

Cetirizine may interact with several medicines. Major Interactions (Avoid): - Alcohol: may increase sedation. - CNS depressants (e.g., benzodiazepines, opioids): risk of excessive drowsiness. - Theophylline: may raise cetirizine plasma levels. Moderate Interactions (Monitor Closely): - Ritonavir: can increase cetirizine exposure. - Antacids containing aluminum or magnesium: may reduce absorption. - Antihypertensives: possible additive hypotensive effect.

Frequently asked questions

What is Letizen S used for?+
Letizen S contains cetirizine, an antihistamine that is used to relieve the symptoms of allergic rhinitis, such as sneezing, runny nose and itchy eyes, as well as to control itching and hives associated with urticaria.
How does cetirizine work?+
Cetirizine works by selectively blocking peripheral histamine H1 receptors. This prevents histamine released during an allergic response from binding to its receptors, thereby reducing vasodilation, increased permeability and nerve stimulation that cause typical allergy symptoms.
What is the usual dose of Letizen S?+
The appropriate dose of Letizen S is determined by a prescriber based on the patient’s age, weight, renal function and the severity of symptoms. Healthcare professionals follow local labeling recommendations when deciding the exact amount and frequency.
Is Letizen S safe during pregnancy or breastfeeding?+
Safety data for cetirizine in pregnancy are limited, so pregnant women should only use Letizen S if the potential benefit outweighs any risk and after consulting their doctor. While small amounts are excreted in breast milk, nursing mothers should seek medical advice before use.
How do I order Letizen S from GNH USA?+
To order Letizen S, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Letizen S compare with other antihistamines?+
Letizen S (cetirizine) is a second‑generation antihistamine that generally causes less sedation than first‑generation agents such as diphenhydramine. Compared with another second‑generation option, loratadine, cetirizine may have a slightly faster onset of action but a similar safety profile.
How should Letizen S be stored and handled?+
Store Letizen S at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture and direct sunlight, and keep out of reach of children.
How is Letizen S administered?+
Letizen S is taken orally, usually with a glass of water. It can be taken with or without food, depending on the prescriber’s advice, and should be swallowed whole without crushing or chewing the tablet.
What are the most serious risks associated with Letizen S?+
The most serious risks include rare allergic reactions such as anaphylaxis, severe skin conditions like Stevens‑Johnson syndrome, and angioedema that can affect breathing. Immediate medical attention is required if any of these symptoms appear.
Who should not use Letizen S?+
Individuals with known hypersensitivity to cetirizine or any component of the formulation should avoid Letizen S. Caution is also advised for patients with severe renal impairment, and it should be used only under medical supervision in pregnant or breastfeeding women.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Cetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Krka, D.D., Novo Mesto
Origin
EU

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