Letizen (Cetirizine Dihydrochloride)

Cetirizine dihydrochloride, the active ingredient in Letizen, is an H1‑receptor antagonist presented as an oral tablet for systemic use. It relieves the nasal and skin symptoms of allergic rhinitis, seasonal hay fever and chronic idiopathic urticaria in both adults and children.\n\nGNH India supplies Letizen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Letizen is an oral antihistamine that acts on the histamine‑mediated allergic pathway.\n\nAllergic rhinitis: reduces sneezing, nasal itching, and runny nose.\nSeasonal allergic rhinitis (hay fever): alleviates eye and nasal itching, congestion and watery discharge.\nChronic idiopathic urticaria: diminishes hives and associated itching.

Adverse reactions may occur with cetirizine use.\n\nCommon Side Effects:\n- Drowsiness\n- Dry mouth\n- Headache\n- Fatigue\n\nSerious or Rare Side Effects:\n- Anaphylactic reaction\n- Stevens‑Johnson syndrome\n- Angioedema

Before using Letizen, consider the following safety points.\n\nPregnancy: consult a healthcare professional; safety data are limited.\nBreastfeeding: use with caution; cetirizine may pass into milk.\nRenal impairment: dose adjustment may be required in reduced kidney function.\nElderly: monitor for increased sedation or confusion.\nDrug interactions: avoid concurrent use with other CNS depressants without medical advice.\nStore at ambient temperature: keep in the original container, protect from moisture and light.

Cetirizine can interact with several medicines; monitoring is advised.\n\nMajor Interactions (Avoid):\n- Alcohol: may increase sedation.\n- Other antihistamines: additive antihistaminic effect.\n- CNS depressants (e.g., benzodiazepines): enhanced drowsiness.\n\nModerate Interactions (Monitor Closely):\n- Theophylline: may raise plasma cetirizine levels.\n- Ritonavir: can increase cetirizine exposure.\n- Ketoconazole: may elevate cetirizine concentrations.