Lescol Mr

Fluvastatin Sodium, the active ingredient in Lescol MR, is a HMG‑CoA reductase inhibitor presented as an oral tablet for oral use. It treats hypercholesterolemia, hyperlipidemia and helps prevent cardiovascular disease in adult patients. GNH USA supplies Lescol MR as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lescol MR, a statin that lowers blood lipids, is indicated for the following conditions: - Hypercholesterolemia: reduces low‑density lipoprotein (LDL) cholesterol levels. - Hyperlipidemia: lowers total cholesterol and triglyceride concentrations. - Prevention of cardiovascular disease: decreases the risk of myocardial infarction, stroke and related events.

Common Side Effects: - Headache: mild to moderate pain in the head region. - Abdominal pain: discomfort or cramping in the stomach area. - Nausea: feeling of queasiness or urge to vomit. - Muscle pain (myalgia): soreness or aching in skeletal muscles. - Constipation: difficulty passing stools. - Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects: - Rhabdomyolysis: severe muscle breakdown that can lead to kidney injury. - Elevated liver enzymes: signs of hepatic injury requiring monitoring. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Myopathy: significant muscle weakness with elevated creatine kinase. - Hepatitis: inflammation of the liver. - Pancreatitis: inflammation of the pancreas.

Before initiating therapy, consider the following precautions: - Monitor liver function: obtain baseline and periodic liver enzyme tests. - Assess muscle symptoms: report unexplained muscle pain or weakness promptly. - Evaluate renal function: adjust use in severe renal impairment. - Avoid in active liver disease: contraindicated in patients with ongoing hepatic injury. - Use caution in pregnancy: safety not established; weigh risks and benefits. - Store at ambient temperature: keep below 25°C, protect from moisture and keep in original packaging.

Fluvastatin may interact with other medicines. Review the following:

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin): may increase fluvastatin exposure. - Gemfibrozil: raises risk of myopathy and rhabdomyolysis. - Cyclosporine: elevates plasma concentrations of fluvastatin.

Moderate Interactions (Monitor Closely): - Antacids (e.g., aluminum hydroxide): can reduce fluvastatin absorption. - Warfarin: fluvastatin may enhance anticoagulant effect; monitor INR regularly.