Lesamor

Hydrochlorothiazide / Telmisartan, the active ingredient in Lesamor, is a thiazide diuretic and angiotensin II receptor blocker presented as a tablet for oral use. It is prescribed to manage hypertension in adult patients, often when monotherapy is insufficient and to improve blood pressure control.

GNH USA supplies Lesamor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to strict quality standards and provides regulatory documentation for each batch. Customers benefit from reliable logistics, competitive pricing, and responsive technical support.

Lesamor, a combination of a thiazide diuretic and an angiotensin II receptor blocker, is indicated for the treatment of hypertension. - Essential hypertension: lowers systolic and diastolic blood pressure to target levels. - Hypertension in patients with diabetes: improves blood pressure control and may provide renal protective benefits. - Hypertension resistant to monotherapy: offers additive antihypertensive effect when combined therapy is required.

Common Side Effects: - Dizziness: may occur due to reduced blood pressure. - Increased urination: result of the diuretic component. - Electrolyte imbalance (low potassium): caused by enhanced sodium excretion.

Serious or Rare Side Effects: - Severe dehydration: can lead to hypotension and renal impairment. - Hyperkalemia or severe hypokalemia: significant electrolyte disturbances. - Angioedema: swelling of face, lips, or airway requiring immediate medical attention. - Hepatic dysfunction: abnormal liver enzymes or jaundice. - Renal impairment: worsening kidney function, especially in patients with pre‑existing disease.

Before initiating therapy, consider the following precautions: - Monitor blood pressure: adjust dosage based on therapeutic response. - Assess renal function: check serum creatinine and eGFR prior to and during treatment. - Check electrolytes: especially potassium and sodium levels. - Avoid use in pregnancy: category D, potential fetal harm. - Caution in elderly patients: increased risk of volume depletion and orthostatic hypotension. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Lesamor may interact with several medicines; review patient medication lists carefully. Major Interactions (Avoid): - Potassium‑sparing diuretics: risk of hyperkalemia. - Lithium: increased lithium concentrations and toxicity. - NSAIDs: may blunt antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - ACE inhibitors: additive risk of renal dysfunction and hyperkalemia. - Other antihypertensives: potential for excessive hypotension. - Cyclosporine: may elevate serum creatinine and reduce drug clearance.