Lercaton Plus

Enalapril maleate and lercanidipine hydrochloride, the active ingredients in Lercaton Plus, are an ACE inhibitor and calcium channel blocker combination presented as a tablet for oral use. It treats hypertension in adult patients.

GNH USA supplies Lercaton Plus as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lercaton Plus is an antihypertensive medication that acts on the renin‑angiotensin system and vascular smooth‑muscle calcium channels.

- Essential hypertension: lowers systolic and diastolic blood pressure to target levels. - Secondary hypertension: assists in controlling elevated blood pressure due to underlying causes. - Isolated systolic hypertension: helps achieve recommended systolic pressure goals.

Common Side Effects: - Dizziness: feeling light‑headed, especially after standing. - Headache: mild to moderate intensity. - Cough: dry, non‑productive cough. - Peripheral edema: swelling of ankles or feet. - Flushing: transient warmth and redness of the skin. - Fatigue: general tiredness.

Serious or Rare Side Effects: - Angioedema: swelling of face, lips, tongue, or throat that may impair breathing. - Severe hypotension: markedly low blood pressure causing faintness. - Liver dysfunction: abnormal liver enzyme elevations. - Neutropenia: reduced white blood cell count increasing infection risk. - Myocardial infarction: rare occurrence of heart attack. - Anaphylaxis: severe allergic reaction requiring immediate medical attention.

Before prescribing Lercaton Plus, clinicians should consider several safety measures. - Blood pressure monitoring: check regularly to avoid excessive hypotension. - Renal function assessment: evaluate kidney status prior to initiation. - ACE inhibitor intolerance: avoid in patients with known hypersensitivity. - Hepatic impairment: use caution in patients with liver disease. - Concomitant potassium‑sparing agents: monitor serum potassium levels. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Lercaton Plus may interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid): - Aliskiren in diabetic patients: combined use can increase risk of renal impairment. - Potassium supplements or potassium‑sparing diuretics: may cause hyperkalaemia. - NSAIDs: can blunt antihypertensive efficacy.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance hypotensive effect. - Lithium: concurrent use can raise lithium concentrations. - Beta‑blockers: may mask tachycardia signs of hypotension.