Lercanidipine Hcl Aurobindo (Lercanidipine Hydrochloride)

Lercanidipine hydrochloride, the active ingredient in Lercanidipine Hcl Aurobindo, is a calcium channel blocker presented as an oral tablet for oral use. It is indicated for the management of essential hypertension in adult patients, helping to lower systolic and diastolic blood pressure.

GNH USA supplies Lercanidipine Hcl Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lercanidipine is used to treat hypertension, a condition characterized by elevated arterial pressure.

- Essential hypertension: reduces systolic and diastolic blood pressure in adults with primary hypertension - Isolated systolic hypertension: helps control elevated systolic pressure in older patients - Hypertension with diabetes: contributes to blood pressure control as part of combination therapy

Lercanidipine may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects: - Headache: mild to moderate pain often occurring after dose initiation - Flushing: transient warmth and redness of the skin - Peripheral edema: swelling of ankles or feet due to fluid accumulation - Dizziness: sensation of light‑headedness, especially when standing quickly

Serious or Rare Side Effects: - Angioedema: swelling of face, lips, tongue that may compromise airway - Severe hypotension: marked drop in blood pressure causing fainting or shock - Hepatic dysfunction: abnormal liver enzymes or hepatitis

Before initiating therapy, clinicians should consider several safety measures.

- Monitor blood pressure: adjust therapy based on regular measurements - Assess liver function: use caution in patients with hepatic impairment - Avoid abrupt discontinuation: may lead to rebound hypertension - Use cautiously in the elderly: increased sensitivity to hypotensive effects - Store at room temperature: keep in original packaging, protect from moisture

Lercanidipine can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma concentrations - Concomitant use with other antihypertensives: risk of excessive hypotension - Grapefruit juice: can raise drug levels and enhance effects

Moderate Interactions (Monitor Closely): - Diuretics: monitor electrolytes and renal function - Beta‑blockers: observe for additive heart‑rate reduction - Antacids containing aluminum or magnesium: may affect absorption if taken simultaneously