Lercanidipina Aurobindo (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipina Aurobindo, is a calcium channel blocker presented as a tablet for oral use. It treats hypertension in adult patients by lowering elevated blood pressure and reducing cardiovascular risk.

GNH USA supplies Lercanidipina Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lercanidipine is a dihydropyridine calcium‑channel blocker used to manage high blood pressure within the cardiovascular disease pathway. - Hypertension: lowers systolic and diastolic pressure to target levels. - Essential hypertension: provides sustained 24‑hour blood pressure control. - Isolated systolic hypertension: reduces pulse pressure and cardiovascular strain.

Lercanidipina Aurobindo may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Headache: mild to moderate intensity. - Flushing: transient warmth and redness of the skin. - Peripheral edema: swelling of the ankles or lower legs. - Dizziness: sensation of light‑headedness, especially after standing. - Tachycardia: increased heart rate. - Fatigue: general feeling of tiredness.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure requiring medical attention. - Myocardial infarction: chest pain or heart attack symptoms. - Hepatic dysfunction: elevated liver enzymes or jaundice. - Angioedema: rapid swelling of face, lips, or airway. - Allergic reactions: rash, itching, or anaphylaxis. - Cardiac arrhythmia: irregular heart rhythm.

Before initiating therapy, clinicians should consider several safety measures. - Monitor blood pressure: assess response after starting or adjusting dose. - Review liver function: check hepatic enzymes periodically. - Assess concomitant antihypertensives: avoid excessive blood pressure reduction. - Caution in elderly patients: start with the lowest effective dose. - Avoid abrupt discontinuation: taper gradually to prevent rebound hypertension. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Lercanidipina Aurobindo can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase plasma concentrations and risk of hypotension. - Potent vasodilators (e.g., nitroglycerin): may cause severe blood pressure fall.

Moderate Interactions (Monitor Closely): - CYP3A4 inducers (e.g., rifampicin, carbamazepine): reduce drug efficacy. - Diuretics: additive antihypertensive effect, monitor electrolytes. - Beta‑blockers: combined effect may lead to excessive blood pressure lowering.