GNH USA

Europe — EMA

Lerakta (Lercanidipine Hydrochloride)

GNH USA supplies Lerakta (Lercanidipine Hydrochloride), a calcium channel blocker for hypertension. Request a quote for global supply.

Lercanidipine Hydrochloride

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1
Pack/s

What is Lercanidipine Hydrochloride?

Lercanidipine Hydrochloride, the active ingredient in Lerakta, is a calcium channel blocker (dihydropyridine) presented as an oral tablet for systemic use. It is prescribed to lower elevated blood pressure in adult patients with hypertension by relaxing vascular smooth muscle and improving arterial compliance.

GNH USA supplies Lerakta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality through stringent manufacturing standards and regulatory compliance across EU and global markets.

What is Lercanidipine Hydrochloride used for?

Lerakta, a calcium channel blocker, is used in the management of hypertension.

Hypertension: reduces systolic and diastolic blood pressure, helping to prevent cardiovascular complications.

What are the side effects of Lercanidipine Hydrochloride?

Lerakta may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects: - Headache - Flushing - Peripheral edema - Dizziness

Serious or Rare Side Effects: - Severe hypotension - Myocardial infarction - Angioedema

What precautions apply to Lercanidipine Hydrochloride?

When prescribing Lerakta, clinicians should consider several safety measures. - Monitor blood pressure regularly: adjust therapy based on response. - Use caution in hepatic impairment: reduced metabolism may increase exposure. - Avoid abrupt discontinuation: taper to prevent rebound hypertension. - Use with caution in elderly patients: increased sensitivity to hypotensive effects. - Contraindicated in severe hypotension: risk of further blood‑pressure drop. - Store at room temperature: keep in the original pack, protect from moisture.

What does Lercanidipine Hydrochloride interact with?

Lerakta can interact with other medicines, requiring attention to the level of risk.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may raise plasma concentrations. - Grapefruit juice: can increase drug levels and enhance hypotensive effect. - Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce efficacy.

Moderate Interactions (Monitor Closely): - Beta‑blockers: additive blood‑pressure lowering effect. - Diuretics: may enhance antihypertensive response. - NSAIDs: can blunt the blood‑pressure‑lowering effect of Lerakta.

Frequently asked questions

What is Lerakta used for?+
Lerakta contains lercanidipine hydrochloride and is indicated for the treatment of hypertension. By lowering elevated systolic and diastolic blood pressure, it helps reduce the risk of cardiovascular events such as stroke and heart attack in adult patients.
How does lercanidipine work?+
Lercanidipine selectively blocks L‑type calcium channels in the smooth muscle of blood vessels. This inhibition prevents calcium‑driven contraction, leading to vasodilation of peripheral arteries, a fall in systemic vascular resistance, and consequently lower arterial pressure.
What is the usual dose of Lerakta?+
The dose of Lerakta is individualized by the prescribing clinician based on the patient’s blood‑pressure profile, age, renal and hepatic function, and concomitant therapies. The prescriber determines the appropriate starting dose and any subsequent titration.
Is Lerakta safe in pregnancy or breastfeeding?+
Safety of lercanidipine during pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.
How do I order Lerakta from GNH USA?+
To place an order, submit an enquiry on the Lerakta product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lerakta compare with amlodipine?+
Both Lerakta (lercanidipine) and amlodipine belong to the dihydropyridine class of calcium‑channel blockers and lower blood pressure by vasodilation. Lercanidipine is more lipophilic, offering a slower onset and longer vascular residence, which may translate into a smoother blood‑pressure profile for some patients.
How should Lerakta be stored?+
Lerakta tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.
How is Lerakta administered?+
Lerakta is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.
What are the most serious risks associated with Lerakta?+
Serious adverse events, although rare, include severe hypotension, myocardial infarction, and angioedema. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, chest pain, swelling of the face or throat, or difficulty breathing.
Who should not use Lerakta?+
Lerakta is contraindicated in patients with severe hypotension, cardiogenic shock, or known hypersensitivity to lercanidipine or any component of the formulation. It should also be used with caution in individuals with significant hepatic impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lercanidipine Hydrochloride
Route
Oral Use
Manufacturer
Zaklady Farmaceutyczne Polpharma S.A.
Origin
EU

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