Lenotac

Piroxicam, the active ingredient in Lenotac, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for skin application. It belongs to the topical anti‑inflammatory/analgesic therapeutic class and is marketed in the European Union. It is used to relieve pain and inflammation associated with musculoskeletal conditions and certain inflammatory skin disorders in adults.

GNH USA supplies Lenotac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is intended for professional healthcare use.

Piroxicam, a topical NSAID, is employed to manage inflammatory and painful conditions of the musculoskeletal and skin systems.

- Osteoarthritis: reduces joint pain and swelling in affected joints. - Rheumatoid arthritis: alleviates joint inflammation and stiffness. - Sprains and strains: provides local pain relief and diminishes swelling. - Inflammatory skin conditions: decreases redness, edema and discomfort when NSAID therapy is indicated.

Topical piroxicam can cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation or burning sensation at the application site. - Pruritus (itching). - Redness or erythema. - Dryness or peeling of the skin. - Mild rash. - Localized swelling.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis). - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Extensive skin ulceration or necrosis. - Systemic NSAID toxicity (e.g., renal impairment). - Hepatic dysfunction. - Cardiovascular events such as hypertension exacerbation.

Before using Lenotac, consider the following safety measures.

- Assess patient history: verify no known hypersensitivity to piroxicam or other NSAIDs. - Avoid use on infected, open, or severely damaged skin. - Apply the lowest effective amount for the shortest duration needed. - Monitor for gastrointestinal symptoms, especially with extensive use. - Do not combine with systemic NSAIDs without medical supervision. - Store at room temperature: keep in the original container, protect from moisture and light.

Piroxicam may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Concurrent systemic NSAIDs: increased risk of gastrointestinal bleeding. - Anticoagulants (e.g., warfarin): heightened bleeding tendency. - Systemic corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible reduction in renal function. - Diuretics: monitor electrolyte balance and renal parameters. - Lithium: potential increase in serum lithium levels.