GNH USA

Europe — EMA

Lendin

GNH USA supplies Lendin (Bilastine), a second‑generation antihistamine for allergic conjunctivitis and seasonal eye symptoms. Request a quote for supply.

Bilastine

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What is Bilastine?

Bilastine, the active ingredient in Lendin, is a second‑generation antihistamine presented as an ocular formulation for topical eye use. It relieves allergic conjunctivitis and seasonal eye allergy symptoms by blocking histamine activity in the eye tissues.

GNH USA supplies Lendin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable, quality‑assured products across Europe, Asia, Africa and the Americas. Our distribution network ensures timely delivery and compliance with local regulatory requirements for each market globally.

What is Bilastine used for?

Bilastine ophthalmic solution is used to treat allergic eye conditions by antagonizing peripheral H1 receptors. - Allergic conjunctivitis: reduces redness, itching and watery discharge in the affected eye. - Seasonal allergic eye symptoms: alleviates itching and swelling caused by pollen or other seasonal allergens. - Ocular allergic reactions: provides relief from eye irritation due to environmental allergens. - Allergic keratoconjunctivitis: helps control inflammation of the cornea and conjunctiva due to allergy. - Vernal keratoconjunctivitis: offers symptomatic relief in seasonal severe allergic eye disease. - Contact lens‑related allergic irritation: reduces itching and redness when lenses trap allergens.

What are the side effects of Bilastine?

Bilastine ocular solution may cause adverse reactions, most of which are mild and transient.

Common Side Effects: - Eye irritation or burning sensation. - Bitter taste after instillation. - Transient headache. - Mild conjunctival redness.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with eyelid swelling. - Ocular edema or increased intra‑ocular pressure. - Persistent visual disturbances. - Corneal ulceration.

What precautions apply to Bilastine?

When using Bilastine eye drops, consider the following precautions to ensure safe and effective therapy. - Prescription use only: follow the ophthalmologist’s instructions for frequency and duration. - Contact lens wear: remove lenses before instillation and wait at least 15 minutes before reinserting. - Monitor for irritation: discontinue if severe eye pain or persistent redness occurs. - Pediatric use: safety in children under 12 years has not been established; use only if advised. - Pregnancy and lactation: consult a healthcare professional before use as data are limited. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Bilastine interact with?

Bilastine may interact with other medicines; awareness of these interactions helps avoid reduced efficacy or increased risk.

Major Interactions (Avoid): - Ketoconazole or other strong CYP3A4 inhibitors: may increase systemic exposure. - Erythromycin or clarithromycin: can raise Bilastine plasma levels. - Anticholinergic eye drops: may exacerbate dry eye symptoms.

Moderate Interactions (Monitor Closely): - Alcohol: may enhance sedation if systemic absorption occurs. - Other antihistamines: concurrent use may increase risk of additive side effects. - Herbal supplements such as St. John’s wort: could affect drug metabolism.

Frequently asked questions

What is Lendin used for?+
Lendin is an ophthalmic formulation containing bilastine that is used to relieve the signs and symptoms of allergic eye conditions such as allergic conjunctivitis and seasonal allergic eye reactions. It works by reducing redness, itching, and watery discharge associated with ocular allergies.
How does bilastine work in the eye?+
Bilastine is a selective peripheral H1‑receptor antagonist. In the eye it binds to H1 receptors on mast cells and blood vessels, blocking histamine‑induced vasodilation, increased permeability, and nerve activation. This inhibition prevents the cascade that produces redness, itching, and swelling in allergic eye disease.
What is the usual dose of Lendin?+
The dosing regimen for Lendin is determined by the prescribing ophthalmologist based on the severity of the allergic condition, patient age, and response to therapy. The prescriber will specify the number of drops per eye and the frequency of administration.
Is Lendin safe during pregnancy or breastfeeding?+
Safety data for bilastine eye drops in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lendin.
How do I order Lendin from GNH USA?+
To place an order, submit an enquiry on the Lendin product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.
How does Lendin compare with other antihistamine eye drops?+
Lendin contains bilastine, a second‑generation H1 antagonist that offers potent anti‑allergic activity with a lower risk of sedation compared with first‑generation agents such as diphenhydramine. Its selective peripheral action provides effective relief of ocular allergy signs while minimizing systemic side effects.
How should Lendin be stored and handled?+
Lendin should be stored at room temperature, preferably below 25 °C, in its original container. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Do not use the product after the expiration date printed on the label.
How is Lendin administered?+
Lendin is applied as eye drops. The patient should wash hands, tilt the head back, gently pull down the lower eyelid to form a pocket, and instill the prescribed number of drops into the conjunctival sac. Close the eye briefly and avoid blinking excessively to allow absorption.
What are the most serious risks associated with Lendin?+
The most serious risks include severe allergic reactions such as anaphylaxis, ocular edema or a significant rise in intra‑ocular pressure, persistent visual disturbances, and rare events like corneal ulceration. Patients should seek immediate medical attention if they experience swelling of the eyelids, sudden vision changes, or intense eye pain.
Who should not use Lendin?+
Lendin should not be used by individuals with known hypersensitivity to bilastine or any excipients in the formulation. It is also contraindicated in patients for whom the prescriber has determined that the risks outweigh the benefits, such as those with uncontrolled severe ocular infections or certain pediatric populations where safety has not been established.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Bilastine
Route
Ocular Use
Manufacturer
Menarini International Operations Luxembourg S.A.
Origin
EU

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