GNH USA

Europe — EMA

Lenalidomidă Stada

GNH USA supplies Lenalidomidă Stada (Lenalidomide), a drug for myeloma, myelodysplastic syndromes and mantle cell lymphoma. Request a quote for supply.

Lenalidomide

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What is Lenalidomide?

Lenalidomide, the active ingredient in Lenalidomidă Stada, is an immunomodulatory imide drug (IMiD) presented as an oral tablet for oral use. It is indicated for the treatment of multiple myeloma, myelodysplastic syndromes, and mantle cell lymphoma in adult patients.

GNH USA supplies Lenalidomidă Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, and pharmacies worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution, shipping products with appropriate documentation to ensure seamless import and clinical use.

What is Lenalidomide used for?

Lenalidomidă Stada is employed in hematologic malignancies that involve abnormal plasma‑cell proliferation.

Multiple myeloma: reduces tumor burden and prolongs progression‑free survival. Myelodysplastic syndromes with del(5q): improves blood counts and lowers transfusion dependence. Mantle cell lymphoma: contributes to disease control when used in combination regimens.

What are the side effects of Lenalidomide?

Lenalidomidă Stada may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Fatigue or weakness. - Nausea, vomiting or loss of appetite. - Diarrhea or constipation. - Rash or pruritus. - Low neutrophil count (neutropenia). - Low platelet count (thrombocytopenia).

Serious or Rare Side Effects: - Thromboembolic events such as deep‑vein thrombosis or pulmonary embolism. - Severe neutropenia or infections requiring hospitalization. - Secondary primary malignancies, including acute leukemias.

What precautions apply to Lenalidomide?

When prescribing Lenalidomidă Stada, clinicians should consider several safety measures to minimize risk.

Pregnancy risk: contraindicated in pregnancy (Category X); ensure effective contraception. Thromboembolism: assess individual risk and consider prophylactic anticoagulation. Hematologic monitoring: perform regular complete blood counts to detect neutropenia or thrombocytopenia. Renal impairment: evaluate renal function and adjust dosing as needed. Drug interactions: review concomitant medications for CYP or anticoagulant effects. Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

What does Lenalidomide interact with?

Lenalidomidă Stada can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Strong CYP3A4 inducers (e.g., rifampin) – may markedly reduce lenalidomide exposure. - Anticoagulants such as warfarin – increased risk of bleeding. - Immunosuppressants (e.g., cyclosporine) – may heighten toxicity.

Moderate Interactions (Monitor Closely): - Antiplatelet agents (e.g., aspirin) – monitor for additive bleeding risk. - Live attenuated vaccines – avoid due to potential immunosuppression. - Other IMiDs (e.g., thalidomide, pomalidomide) – concurrent use is not recommended.

Frequently asked questions

What is Lenalidomidă Stada used for?+
Lenalidomidă Stada contains lenalidomide, an immunomodulatory agent indicated for the treatment of adult patients with multiple myeloma, myelodysplastic syndromes that have a del(5q) chromosomal abnormality, and mantle cell lymphoma, usually as part of a combination chemotherapy regimen.
How does lenalidomide work?+
Lenalidomide binds to the cereblon component of the CRL4‑CRBN E3 ubiquitin ligase complex, causing selective degradation of transcription factors Ikaros and Aiolos. This modulates cytokine release, enhances T‑cell and NK‑cell immune responses, and inhibits angiogenesis, together producing anti‑cancer activity in plasma‑cell disorders.
What is the usual dose of Lenalidomidă Stada?+
The specific dose and schedule of Lenalidomidă Stada are determined by the treating physician based on the patient’s diagnosis, disease stage, renal function, and concomitant therapies. Prescribers follow approved labeling and clinical guidelines to individualise therapy.
Is Lenalidomidă Stada safe in pregnancy or breastfeeding?+
Lenalidomidă Stada is classified as pregnancy Category X, meaning it is contraindicated in pregnancy because of a high risk of fetal harm. Women of child‑bearing potential must use effective contraception, and breastfeeding is not recommended while receiving the drug.
How do I order Lenalidomidă Stada from GNH USA?+
To order Lenalidomidă Stada, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Lenalidomidă Stada compare with the main alternative drug or class?+
The primary alternatives to lenalidomide are thalidomide and pomalidomide, which belong to the same immunomodulatory imide drug (IMiD) class. Lenalidomide generally offers a more favorable safety profile than thalidomide, with lower rates of peripheral neuropathy, while providing comparable anti‑myeloma efficacy. Pomalidomide is often reserved for patients who have progressed after lenalidomide therapy.
How should Lenalidomidă Stada be stored and handled?+
Lenalidomidă Stada tablets should be stored at ambient temperature, preferably below 25 °C, in the original blister or bottle, protected from moisture, light and excessive heat. Keep the container tightly closed and out of reach of children.
How is Lenalidomidă Stada given or administered?+
Lenalidomidă Stada is administered orally, usually once daily, with or without food, as directed by the prescribing clinician. The tablets should be swallowed whole with water and not crushed or chewed unless specifically instructed.
What are the most serious risks to watch for while taking Lenalidomidă Stada?+
The most serious risks include thromboembolic events (deep‑vein thrombosis, pulmonary embolism), severe neutropenia or infections, and the development of secondary primary malignancies such as acute leukemias. Patients should be monitored closely for signs of clotting, fever, or unexplained bleeding.
Who should not use Lenalidomidă Stada?+
Lenalidomidă Stada should not be used by pregnant women, individuals with known hypersensitivity to lenalidomide or any excipients, and patients with uncontrolled severe renal impairment unless dose adjustments are made. Caution is also advised for patients with a history of thromboembolic disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Lenalidomide
Route
Oral Use
Manufacturer
Stada M&d S.R.L.
Origin
EU

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