Lekadol

Paracetamol, the active ingredient in Lekadol, is an analgesic presented as an oral dosage form for oral use. It reduces pain and fever and is commonly used in adults and children for mild to moderate discomfort, and is available over the counter in many markets.

GNH USA supplies Lekadol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers, including bulk shipments and customized packaging options.

Paracetamol is an analgesic/antipyretic that acts on the central nervous system to relieve pain and reduce fever.

- Pain: provides relief of mild to moderate pain such as headache, toothache, and musculoskeletal discomfort. - Fever: lowers elevated body temperature in febrile conditions. - Post‑operative pain: helps manage discomfort after surgical procedures. - Cold symptoms: alleviates discomfort associated with common cold and flu.

Paracetamol may cause adverse reactions, ranging from mild to serious, although it is generally well tolerated.

Common Side Effects: - Nausea - Skin rash - Headache - Dizziness

Serious or Rare Side Effects: - Severe skin reactions (e.g., Stevens‑Johnson syndrome, toxic epidermal necrolysis) - Hepatotoxicity, especially with overdose - Blood disorders such as agranulocytosis - Anaphylactic reactions

Paracetamol should be used with caution in certain clinical situations to minimize risk.

- Assess liver function: avoid use in patients with severe hepatic impairment. - Limit alcohol consumption: concurrent intake may increase liver risk. - Monitor dosage in children: ensure weight‑based dosing as prescribed. - Avoid prolonged high‑dose therapy: risk of liver injury increases with duration. - Store at ambient temperature: keep below 25°C in original packaging, protect from moisture.

Paracetamol can interact with several medicines, requiring attention to avoid adverse effects.

Major Interactions (Avoid): - Alcohol: combined use heightens risk of liver damage. - Warfarin: may potentiate anticoagulant effect, increasing bleeding risk. - Carbamazepine: induces metabolism, reducing paracetamol efficacy.

Moderate Interactions (Monitor Closely): - Isoniazid: may increase hepatotoxic potential. - Phenobarbital: may lower plasma concentrations of paracetamol. - Oral contraceptives: may affect hepatic enzyme activity, requiring monitoring.