GNH USA

Europe — EMA

Lekadol Complex

GNH USA supplies Lekadol Complex (Ibuprofen/Paracetamol), a NSAID/analgesic for pain relief, fever reduction and mild inflammation.

Ibuprofen, Paracetamol

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What is Ibuprofen, Paracetamol?

Ibuprofen, the active ingredient in Lekadol Complex, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for systemic use. Together with paracetamol, the formulation provides analgesic and antipyretic effects, helping to relieve mild to moderate pain, reduce fever, and address mild inflammation in adults.

GNH USA supplies Lekadol Complex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and offers reliable global distribution.

What is Ibuprofen, Paracetamol used for?

Lekadol Complex combines ibuprofen and paracetamol to manage conditions involving pain, fever, and mild inflammation through anti‑inflammatory and antipyretic mechanisms.

- Pain relief: alleviates mild to moderate acute pain such as headache, toothache, or musculoskeletal discomfort. - Fever reduction: lowers elevated body temperature associated with viral or bacterial infections. - Mild inflammation: reduces localized swelling and discomfort in conditions like minor sprains or strains.

What are the side effects of Ibuprofen, Paracetamol?

Lekadol Complex may cause adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Nausea: mild stomach upset or queasiness. - Dyspepsia: indigestion or heartburn. - Headache: transient head discomfort. - Dizziness: light‑headed sensation. - Rash: mild skin redness or itching. - Elevated liver enzymes: temporary increase detected in blood tests.

Serious or Rare Side Effects: - Gastrointestinal bleeding: serious bleeding in the stomach or intestines. - Severe allergic reaction: anaphylaxis with swelling, hives, or difficulty breathing. - Liver injury: rare but potentially serious hepatic dysfunction. - Kidney impairment: reduced renal function, especially with prolonged use. - Stevens‑Johnson syndrome: severe skin and mucous membrane reaction. - Blood disorders: rare thrombocytopenia or leukopenia.

What precautions apply to Ibuprofen, Paracetamol?

Before using Lekadol Complex, consider the following precautions to minimize risk.

- Medical history review: assess for ulcers, liver disease, kidney impairment, asthma, or cardiovascular conditions. - Concomitant NSAID use: avoid taking other NSAIDs or aspirin to reduce gastrointestinal risk. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Alcohol consumption: limit alcohol intake as it may increase liver toxicity. - Duration of therapy: use the lowest effective dose for the shortest necessary period. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen, Paracetamol interact with?

Lekadol Complex can interact with other medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - Lithium: ibuprofen may raise lithium serum levels. - Methotrexate: ibuprofen can reduce clearance, raising toxicity risk. - SSRIs (e.g., sertraline): combined use may increase bleeding tendency.

Moderate Interactions (Monitor Closely): - Antihypertensives (e.g., ACE inhibitors): possible reduction in blood pressure control. - Diuretics: risk of reduced renal function. - Corticosteroids: additive risk of gastrointestinal ulceration. - Alcohol: enhanced liver strain. - Cyclosporine: possible increased nephrotoxicity.

Frequently asked questions

What is Lekadol Complex used for?+
Lekadol Complex is an over‑the‑counter oral medication that combines ibuprofen and paracetamol to provide relief from mild to moderate pain, reduce fever, and address mild inflammation. It is commonly used for headaches, toothaches, musculoskeletal aches, and febrile conditions associated with viral or bacterial infections.
How does ibuprofen work in Lekadol Complex?+
Ibuprofen, one of the active ingredients, works by non‑selectively inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This reduces the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever, thereby delivering anti‑inflammatory, analgesic, and antipyretic effects throughout the body.
What is the usual dose of Lekadol Complex?+
The appropriate dose of Lekadol Complex is determined by a qualified healthcare professional based on the individual’s age, weight, medical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount indicated on the product label.
Is Lekadol Complex safe during pregnancy or breastfeeding?+
Safety during pregnancy or lactation has not been definitively established for the combination of ibuprofen and paracetamol. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Lekadol Complex to weigh potential benefits against possible risks.
How do I order Lekadol Complex from GNH USA?+
To order Lekadol Complex, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.
How does Lekadol Complex compare with ibuprofen alone?+
Lekadol Complex combines ibuprofen with paracetamol, offering a broader analgesic and antipyretic profile than ibuprofen alone. The addition of paracetamol can enhance pain relief and fever reduction while allowing lower doses of each component, potentially reducing the risk of side effects associated with higher doses of a single agent.
How should Lekadol Complex be stored?+
Lekadol Complex should be stored at room temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.
How is Lekadol Complex administered?+
Lekadol Complex is taken orally. Swallow the tablet whole with a full glass of water, preferably with food or after a meal to lessen gastrointestinal discomfort. Do not crush, chew, or split the tablet unless specifically directed by a healthcare professional.
What are the most serious risks to watch for with Lekadol Complex?+
Serious risks include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, liver injury, and kidney impairment. Patients should seek immediate medical attention if they notice symptoms like black stools, vomiting blood, rash with swelling, jaundice, or sudden decrease in urine output.
Who should not use Lekadol Complex?+
Individuals with a known hypersensitivity to ibuprofen, paracetamol, or any excipients in the formulation should avoid Lekadol Complex. It is also contraindicated in patients with active peptic ulcer disease, severe liver or kidney impairment, uncontrolled asthma triggered by NSAIDs, and those taking anticoagulants without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen, Paracetamol
Route
Oral Use
Manufacturer
Sandoz Pharmaceuticals D.D.
Origin
EU

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