Europe — EMA
Lekadol Combo
GNH USA supplies Lekadol Combo (Phenylephrine Hydrochloride / Paracetamol), a combination analgesic and nasal decongestant for headache, fever, minor aches
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What is Phenylephrine Hydrochloride, Paracetamol?
Phenylephrine Hydrochloride and Paracetamol, the active ingredients in Lekadol Combo, are a combination analgesic and nasal decongestant presented as an oral tablet for over‑the‑counter use. They provide relief from headache, fever, minor aches and pains, and nasal congestion in adults and children.
GNH USA supplies Lekadol Combo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent product availability and regulatory support across EU and other markets.
What is Phenylephrine Hydrochloride, Paracetamol used for?
Lekadol Combo, a combination analgesic and nasal decongestant, is indicated for the following conditions:
- Headache: temporary relief of tension‑type or mild migraine pain. - Fever: reduction of elevated body temperature associated with common infections. - Minor aches and pains: alleviation of discomfort from muscle strain, backache, toothache or similar mild conditions. - Nasal congestion: clearing of blocked nasal passages caused by colds, sinusitis or allergic rhinitis.
What are the side effects of Phenylephrine Hydrochloride, Paracetamol?
Common Side Effects: - Nausea: mild stomach upset that may occur after oral intake. - Dizziness: transient light‑headedness, especially when standing quickly. - Dry mouth: reduced salivation leading to a feeling of thirst. - Mild headache: occasional headache unrelated to the treated condition.
Serious or Rare Side Effects: - Allergic rash or swelling: signs of hypersensitivity such as hives, facial edema or itching. - Severe hypertension: marked increase in blood pressure, particularly in susceptible individuals. - Liver function abnormalities: elevated liver enzymes indicating possible hepatic stress. - Anaphylactic reaction: rare but life‑threatening systemic allergic response requiring immediate medical attention.
What precautions apply to Phenylephrine Hydrochloride, Paracetamol?
Before using Lekadol Combo, consider the following precautions: - Pregnancy: consult a healthcare professional to assess risk versus benefit. - Breastfeeding: use only if the expected benefit to the infant outweighs potential risk. - Cardiovascular disease: avoid excessive phenylephrine in patients with hypertension or heart disease. - Liver disease: limit paracetamol intake and monitor hepatic function. - Drug interactions: review all concurrent medications for possible interactions. - Store at ambient temperature: keep below 25 °C, retain in the original packaging, and protect from moisture.
What does Phenylephrine Hydrochloride, Paracetamol interact with?
Lekadol Combo may interact with other medicines as follows:
Major Interactions (Avoid): - Monoamine oxidase inhibitors: risk of hypertensive crisis when combined with phenylephrine. - Other sympathomimetic agents: additive vasoconstrictive effects may raise blood pressure. - Additional paracetamol‑containing products: increased risk of hepatotoxicity. - Warfarin: paracetamol may potentiate anticoagulant effect and raise INR.
Moderate Interactions (Monitor Closely): - Antihypertensive drugs: phenylephrine may diminish their efficacy. - Selective serotonin reuptake inhibitors: potential for serotonin‑related adverse events. - Alcohol: combined use can increase liver stress and enhance sedation. - CYP2E1 inducers: may alter paracetamol metabolism, affecting safety profile.
Frequently asked questions
What is Lekadol Combo used for?+
How does phenylephrine hydrochloride work?+
What is the usual dose of Lekadol Combo?+
Is Lekadol Combo safe to use during pregnancy or breastfeeding?+
How do I order Lekadol Combo from GNH USA?+
How does Lekadol Combo compare with separate phenylephrine or paracetamol products?+
What are the storage and handling requirements for Lekadol Combo?+
How is Lekadol Combo administered?+
What are the most serious risks associated with Lekadol Combo?+
Who should not use Lekadol Combo?+
Product details
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