GNH USA

Europe — EMA

Lekadol Combo

GNH USA supplies Lekadol Combo (Phenylephrine/Paracetamol), an analgesic/antipyretic decongestant for headache, fever and nasal congestion. Request a quote.

Phenylephrine Hydrochloride, Paracetamol

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What is Phenylephrine Hydrochloride, Paracetamol?

Phenylephrine Hydrochloride, the active ingredient in Lekadol Combo, is a combination analgesic/antipyretic and decongestant presented as an oral tablet for oral use. It provides relief from pain, fever, and nasal congestion associated with common colds and similar conditions.

GNH USA supplies Lekadol Combo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams across multiple markets worldwide. The company adheres to stringent quality standards and provides regulatory support for import and distribution. This ensures timely delivery and product integrity.

What is Phenylephrine Hydrochloride, Paracetamol used for?

Lekadol Combo, a combination analgesic/antipyretic and decongestant, is used to manage symptoms of common cold and related conditions.

- Headache: reduces pain associated with tension or mild migraine. - Fever: lowers elevated body temperature during infectious or inflammatory states. - Common cold symptoms: alleviates overall discomfort such as aches and chills. - Nasal congestion: eases blocked nasal passages by shrinking swollen mucosal vessels.

What are the side effects of Phenylephrine Hydrochloride, Paracetamol?

Adverse reactions may occur with oral use of Lekadol Combo.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Dizziness: transient light‑headedness. - Headache: occasional worsening of head pain. - Dry mouth: reduced salivation. - Insomnia: difficulty falling asleep. - Mild rash: skin irritation or redness.

Serious or Rare Side Effects: - Allergic reaction: hives, swelling, or difficulty breathing. - Hypertension: sudden increase in blood pressure. - Liver injury: elevated liver enzymes or jaundice. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiac arrhythmia: irregular heart rhythm in susceptible individuals.

What precautions apply to Phenylephrine Hydrochloride, Paracetamol?

Before using Lekadol Combo, consider the following safety measures.

- Pregnancy: consult a healthcare professional before use. - Liver disease: avoid or use only under medical supervision. - Hypertension: monitor blood pressure regularly. - Drug interactions: review all concurrent medications with a pharmacist. - Age restrictions: not recommended for children under the specified age without guidance. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.

What does Phenylephrine Hydrochloride, Paracetamol interact with?

Lekadol Combo may interact with other medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis. - Warfarin: increased bleeding risk due to paracetamol. - Monoamine oxidase inhibitors: heightened cardiovascular effects. - Other decongestants: potential for excessive vasoconstriction. - Antihypertensive agents: may reduce efficacy.

Moderate Interactions (Monitor Closely): - Alcohol: enhanced liver toxicity. - SSRIs or SNRIs: possible increase in blood pressure. - Other analgesics: risk of cumulative dosing. - Antacids: may affect absorption. - Diuretics: monitor electrolyte balance.

Frequently asked questions

What is Lekadol Combo used for?+
Lekadol Combo is an over‑the‑counter oral tablet that combines phenylephrine and paracetamol to relieve headache, reduce fever, and ease nasal congestion associated with common colds and mild upper‑respiratory infections.
How does phenylephrine work in Lekadol Combo?+
Phenylephrine is an alpha‑1 adrenergic agonist; it narrows the blood vessels in the nasal mucosa, decreasing swelling and allowing the airways to open, which relieves congestion.
What is the usual dose of Lekadol Combo?+
The appropriate dose of Lekadol Combo is determined by a qualified prescriber based on the patient’s age, weight, and clinical condition. Patients should follow the healthcare professional’s instructions and the product label.
Is Lekadol Combo safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.
How do I order Lekadol Combo from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lekadol Combo compare with other cold‑relief medicines?+
Compared with single‑ingredient products, Lekadol Combo offers both analgesic/antipyretic action (paracetamol) and decongestant activity (phenylephrine) in one tablet, simplifying dosing and potentially improving adherence for patients needing relief from multiple symptoms.
What are the storage requirements for Lekadol Combo?+
Store Lekadol Combo at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, excessive heat, and direct sunlight to maintain potency.
How is Lekadol Combo administered?+
Lekadol Combo is taken orally with a full glass of water. It may be taken with or without food, unless the prescribing clinician advises otherwise.
What are the most serious risks associated with Lekadol Combo?+
Serious risks include allergic reactions such as hives or swelling, significant hypertension, and rare but severe liver injury. Patients should seek immediate medical attention if they experience difficulty breathing, rash, jaundice, or a sudden rise in blood pressure.
Who should not use Lekadol Combo?+
Individuals with known hypersensitivity to phenylephrine, paracetamol, or any excipients, those with uncontrolled hypertension, severe liver disease, or who are taking contraindicated medications (e.g., MAO inhibitors) should avoid using Lekadol Combo unless directed by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Paracetamol
Route
Oral Use
Manufacturer
Sandoz D.O.O.
Origin
EU

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