Lecrolyn

Sodium cromoglicate, the active ingredient in Lecrolyn, is a mast cell stabilizer presented as a solution for ocular use. It helps relieve allergic eye symptoms in patients with ocular allergy.

GNH USA supplies Lecrolyn as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Sodium cromoglicate is used to manage allergic ocular conditions by stabilizing mast cells.

Allergic conjunctivitis: reduces itching, redness, and tearing associated with seasonal or perennial eye allergies. Vernal keratoconjunctivitis: helps control chronic inflammation in patients with this seasonal allergic disease. Atopic keratoconjunctivitis: may be used as an adjunct to lessen ocular surface inflammation in atopic individuals.

Sodium cromoglicate is generally well tolerated, but ocular administration can produce local reactions.

Common Side Effects: - Transient burning or stinging sensation upon instillation. - Mild eye irritation or foreign‑body feeling. - Temporary blurred vision that resolves quickly. - Increased tearing or watery discharge. - Mild headache related to eye strain.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angioedema of the eyelid). - Persistent eye pain or worsening redness. - Corneal ulceration or epithelial defect. - Vision loss or sudden visual disturbance. - Anaphylaxis (extremely rare).

When using Lecrolyn, consider the following safety measures.

Avoid use in patients with known hypersensitivity to sodium cromoglicate or any formulation excipients. Do not wear contact lenses during treatment; remove them before each dose and wait at least 15 minutes before reinserting. Monitor for worsening ocular symptoms; discontinue and seek medical advice if irritation persists. Inform the prescriber of any concurrent ocular infections or recent eye surgery. Store below 25°C: keep in the original container, protect from moisture and light, and do not freeze.

Sodium cromoglicate has limited systemic absorption, but ocular co‑medications may influence its safety profile.

Major Interactions (Avoid): - None identified: no major drug‑drug interactions have been reported for ocular sodium cromoglicate.

Moderate Interactions (Monitor Closely): - Concurrent use with other mast cell stabilizers may increase local irritation. - Co‑administration with topical corticosteroids could mask signs of infection. - Use with certain contact lens cleaning solutions may affect drug stability.