Lecrolyn Sine

Sodium Cromoglicate, the active ingredient in Lecrolyn Sine, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis, ocular itching and other mast cell‑mediated eye inflammation in both adults and children.

GNH USA supplies Lecrolyn Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Sodium Cromoglicate is used to treat ocular allergic conditions by stabilizing mast cells and preventing mediator release.

Allergic conjunctivitis: reduces redness, itching and swelling of the conjunctiva. Ocular itching: relieves itch associated with allergic eye disease. Mast cell‑mediated ocular inflammation: controls inflammation and helps prevent symptom recurrence.

Adverse reactions are generally mild and related to local ocular irritation.

Common Side Effects: - Transient eye burning or stinging on instillation. - Mild ocular redness or hyperemia. - Blurred vision that resolves quickly. - Foreign‑body sensation. - Temporary tearing.

Serious or Rare Side Effects: - Allergic reaction with eyelid swelling or angioedema. - Severe eye pain or corneal ulceration. - Vision loss. - Anaphylaxis (extremely rare). - Persistent intraocular inflammation.

Before prescribing Lecrolyn Sine, clinicians should consider several safety aspects.

Assess patient history: confirm diagnosis of allergic ocular disease. Avoid use in patients with known hypersensitivity to sodium cromoglicate. Do not use with contact lenses unless advised by an eye care professional. Monitor for worsening symptoms; discontinue if severe irritation occurs. Store at room temperature: keep in the original container, protect from light and moisture.

Sodium Cromoglicate may interact with other ophthalmic agents; awareness of potential interactions helps maintain safety.

Major Interactions (Avoid): - Concurrent use with ocular anesthetics may increase corneal toxicity. - Co‑administration with other mast cell stabilizers offers no added benefit. - Use with preservative‑containing drops may heighten irritation.

Moderate Interactions (Monitor Closely): - Antihistamine eye drops may reduce overall efficacy. - Systemic antihistamines might lessen ocular response. - Combined use with topical steroids could raise intra‑ocular pressure risk.