GNH USA

Europe — EMA

Lecrolyn Sine

GNH USA supplies Lecrolyn Sine (Sodium Cromoglicate), a stabilizer for conjunctivitis, ocular itching and redness due to eye disease. Request a quote.

Sodium Cromoglicate

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What is Sodium Cromoglicate?

Sodium cromoglicate, the active ingredient in Lecrolyn Sine, is a mast cell stabilizer presented as eye drops for ocular use. It treats allergic conjunctivitis, ocular itching and redness caused by allergic eye disease, helping to reduce inflammation and discomfort in the eyes, and is approved for prescription use in the European Union.

GNH USA supplies Lecrolyn Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for global distribution.

What is Sodium Cromoglicate used for?

Lecrolyn Sine, a mast cell stabilizer, acts on allergic eye disease pathways to alleviate symptoms. - Allergic conjunctivitis: Reduces ocular inflammation and itching associated with allergic reactions. - Ocular itching: Provides relief from itchiness caused by allergic eye disease. - Redness due to allergic eye disease: Decreases hyperemia and discomfort in the affected eye.

What are the side effects of Sodium Cromoglicate?

Sodium cromoglicate eye drops may cause ocular or systemic reactions, although most patients tolerate the medication well.

Common Side Effects: - Transient burning or stinging sensation upon instillation - Mild eye redness - Temporary blurred vision - Tear film instability

Serious or Rare Side Effects: - Allergic contact dermatitis of the eyelid - Severe ocular inflammation - Vision loss - Systemic hypersensitivity reaction

What precautions apply to Sodium Cromoglicate?

When prescribing Lecrolyn Sine, consider the following safety measures. - Pregnancy: Safety not established; use only if clearly needed. - Breastfeeding: Unknown; consider risk vs benefit. - Contact lenses: Remove before administration and wait before reinserting. - Concurrent ocular infection: Evaluate before use. - Allergy to cromoglicate: Contraindicated. - Store at room temperature: keep in original container, protect from light and moisture.

What does Sodium Cromoglicate interact with?

Sodium cromoglicate has a low potential for drug‑drug interactions, but monitor the following.

Major Interactions (Avoid): - Concurrent use with ocular prostaglandin analogs may diminish anti‑inflammatory effect. - Combination with preservative‑rich eye drops may increase ocular irritation.

Moderate Interactions (Monitor Closely): - Use with other mast cell stabilizers may not provide additional benefit. - Co‑administration with topical antihistamines may alter symptom control. - Systemic antihistamines may affect overall allergic response, requiring clinical observation.

Frequently asked questions

What is Lecrolyn Sine used for?+
Lecrolyn Sine is an ophthalmic solution containing sodium cromoglicate, indicated for the treatment of allergic conjunctivitis, ocular itching and redness caused by allergic eye disease. It works by stabilising mast cells in the eye to reduce inflammation and discomfort.
How does sodium cromoglicate work in the eye?+
Sodium cromoglicate stabilises mast cells on the ocular surface, preventing calcium‑dependent degranulation. This blocks the release of histamine, prostaglandins and other inflammatory mediators, thereby reducing vasodilation, itching and redness associated with allergic eye reactions.
What is the usual dose of Lecrolyn Sine?+
The dosing regimen for Lecrolyn Sine is determined by the prescribing clinician based on the severity of the allergic eye condition, patient age and response to therapy. The prescriber will provide specific instructions on the number of drops and frequency of administration.
Is Lecrolyn Sine safe during pregnancy or breastfeeding?+
Safety data for sodium cromoglicate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.
How do I order Lecrolyn Sine from GNH USA?+
To order Lecrolyn Sine, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lecrolyn Sine compare with other antiallergic eye drops?+
Lecrolyn Sine contains sodium cromoglicate, a mast cell stabiliser, whereas many alternative eye drops use antihistamines or non‑steroidal anti‑inflammatory agents. Sodium cromoglicate works upstream by preventing mediator release, offering a different safety profile and may be preferred when a non‑sedating, locally acting option is desired.
What are the storage requirements for Lecrolyn Sine?+
Lecrolyn Sine should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from direct light and moisture, and keep the cap tightly closed when not in use to maintain product stability.
How is Lecrolyn Sine administered?+
The product is supplied as sterile eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. The eyes should be closed gently for a few seconds to allow absorption.
What are the most serious risks associated with Lecrolyn Sine?+
Serious but rare risks include allergic contact dermatitis of the eyelid, severe ocular inflammation, vision loss, and systemic hypersensitivity reactions. Patients should seek immediate medical attention if they experience significant swelling, pain, visual changes or systemic allergic symptoms.
Who should not use Lecrolyn Sine?+
Lecrolyn Sine is contraindicated in individuals with a known hypersensitivity to sodium cromoglicate or any of the formulation excipients. It should also be avoided in patients with active ocular infections until the infection is adequately treated.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Sodium Cromoglicate
Route
Ocular Use
Manufacturer
Santen Oy
Origin
EU

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