Lecrolyn Sine

Sodium Cromoglicate, the active ingredient in Lecrolyn Sine, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It helps manage allergic conjunctivitis and other ocular allergy conditions by reducing the release of histamine and inflammatory mediators in the eye, providing relief from itching, redness, and swelling associated with allergic reactions.

GNH USA supplies Lecrolyn Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lecrolyn Sine is a mast cell stabilizer indicated for ocular allergy conditions and works by preventing mast‑cell degranulation.

- Allergic conjunctivitis: reduces ocular itching, redness and swelling by stabilizing mast cells. - Seasonal allergic conjunctivitis: provides symptom control during pollen seasons. - Vernal keratoconjunctivitis: helps lessen chronic inflammation and discomfort in affected eyes.

Common Side Effects: - Transient burning or stinging sensation upon instillation. - Mild ocular irritation or foreign‑body feeling. - Temporary blurred vision that resolves quickly. - Increased tearing or watery eyes. - Mild conjunctival hyperemia. - Slight eyelid edema.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angioedema of the eyelid). - Persistent eye pain or photophobia. - Vision loss or sudden decrease in visual acuity. - Corneal ulceration or epithelial defect. - Anaphylaxis (extremely rare). - Persistent intra‑ocular inflammation.

Before using Lecrolyn Sine, consider the following precautions: - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Contact lens wearers: remove lenses before instillation and wait several minutes before reinserting. - Active ocular infection: avoid use until infection is resolved. - Avoid contamination: use single‑dose containers and discard any remaining solution after the recommended period. - Store at room temperature: keep in the original container, protect from light and moisture.

Lecrolyn Sine has a limited interaction profile, but the following should be considered.

Major Interactions (Avoid): - Concurrent use with ophthalmic solutions containing benzalkonium chloride: may increase ocular irritation. - Duplicate therapy with other mast cell stabilizers: avoid overlapping treatment.

Moderate Interactions (Monitor Closely): - Combination with topical antihistamine eye drops: monitor for additive dryness. - Use with corticosteroid eye drops: watch intra‑ocular pressure. - Co‑administration with contact lens cleaning solutions containing preservatives: may cause discomfort.