Lecalcif

Colecalciferol, the active ingredient in Lecalcif, is a Vitamin D3 presented as an oral supplement for oral use. It helps correct vitamin D deficiency and supports bone mineralization in individuals at risk of osteomalacia, rickets, or osteoporosis. The formulation provides reliable bioavailability to enhance calcium and phosphate absorption from the gastrointestinal tract.

GNH USA supplies Lecalcif as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lecalcif (colecalciferol) is used in the management of conditions related to inadequate vitamin D status. - Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels to support calcium balance. - Osteoporosis prevention: contributes to bone mineral density maintenance and reduces fracture risk in at‑risk populations. - Rickets: supplies essential vitamin D to promote proper bone growth and mineralization in children.

Lecalcif may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset reported in some users. - Constipation: occasional difficulty with bowel movements. - Headache: transient head pain without other neurological signs. - Fatigue: feeling of tiredness not linked to other causes. - Mild hypercalcemia: slight elevation of blood calcium without symptoms. - Dry mouth: reduced salivation.

Serious or Rare Side Effects: - Hypercalcemia with symptoms: severe calcium elevation causing nausea, vomiting, polyuria, and cardiac arrhythmias. - Nephrolithiasis: formation of kidney stones due to excess calcium. - Allergic reactions: rash, itching, swelling, or anaphylaxis in rare cases.

Before using Lecalcif, consider the following precautions to ensure safe and effective therapy. - Baseline assessment: measure serum 25‑hydroxyvitamin D and calcium levels prior to initiation. - Monitoring: repeat calcium and vitamin D tests periodically during treatment. - Renal impairment: adjust dosage or avoid use in patients with severe kidney disease. - Concomitant calcium supplements: limit additional calcium intake to prevent hypercalcemia. - Pregnancy and lactation: use only if clearly needed and under medical supervision. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Lecalcif can interact with other medicines, altering calcium balance or vitamin D metabolism.

Major Interactions (Avoid): - Thiazide diuretics: may increase risk of hypercalcemia. - High‑dose vitamin A: combined excess can cause hypercalcemia. - Calcium‑containing antacids: can lead to excessive calcium levels.

Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., phenytoin, phenobarbital): may accelerate vitamin D metabolism, reducing efficacy. - Glucocorticoids: can impair vitamin D activation and calcium absorption. - Cholesterol‑lowering agents (e.g., cholestyramine, orlistat): may decrease intestinal absorption of vitamin D. - Bisphosphonates: concurrent use requires monitoring of calcium status.