Lecalcif

Colecalciferol, the active ingredient in Lecalcif, is a vitamin D presented as an oral supplement for oral use. It is used to correct vitamin D deficiency and to support bone health in individuals at risk of osteomalacia or rickets, especially in populations with limited sun exposure.

GNH USA supplies Lecalcif as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution for this vitamin D product.

Lecalcif (colecalciferol) is used to address disorders related to insufficient vitamin D activity.

- Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels, improving calcium balance. - Osteomalacia and rickets prevention: supports bone mineralization to prevent softening of bones in adults and children. - General bone health support: contributes to maintaining bone density and reducing fracture risk in at‑risk individuals.

Oral colecalciferol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Hypercalcemia: mild elevation of blood calcium causing fatigue or nausea. - Nausea: occasional stomach upset after taking the supplement. - Headache: transient mild headache episodes.

Serious or Rare Side Effects: - Severe hypercalcemia: may result in cardiac arrhythmia or renal dysfunction. - Kidney stones: formation of calcium deposits in the urinary tract. - Allergic reactions: rash, itching, swelling, or rare anaphylaxis.

When using Lecalcif, consider the following precautions to ensure safe and effective therapy.

- Serum calcium monitoring: check calcium levels before and during therapy in patients at risk of hypercalcemia. - Renal impairment caution: adjust dose or avoid use in severe kidney disease. - High calcium intake: avoid excessive dietary calcium or calcium supplements concurrently. - Granulomatous disease awareness: conditions such as sarcoidosis may increase sensitivity to vitamin D. - Pregnancy and lactation: use only if prescribed after risk‑benefit assessment. - Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Colecalciferol may interact with certain medicines; the following interactions are recognized.

Major Interactions (Avoid): - Thiazide diuretics: can increase risk of hypercalcemia. - High‑dose calcium supplements: may cause excessive calcium accumulation. - Vitamin A excess: combined toxicity leading to hypercalcemia.

Moderate Interactions (Monitor Closely): - Corticosteroids: may reduce vitamin D effectiveness, requiring dose adjustment. - Anticonvulsants (e.g., phenytoin, carbamazepine): increase vitamin D metabolism, potentially lowering levels. - Cholesterol‑lowering agents (e.g., cholestyramine): may impair absorption of fat‑soluble vitamins.