GNH USA

Europe — EMA

Laxido

GNH USA supplies Laxido (Macrogol 3350), an osmotic laxative for chronic constipation and bowel preparation before colonoscopy.

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

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What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350, the active ingredient in Laxido, is an osmotic laxative presented as an oral powder for solution for oral use. It is used to relieve constipation and to aid bowel cleansing before diagnostic procedures. GNH USA supplies Laxido as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 used for?

Laxido is an osmotic laxative that works within the gastrointestinal tract to manage constipation and assist bowel preparation. - Chronic constipation: softens stool and increases bowel frequency in adults and children with persistent constipation. - Opioid‑induced constipation: provides effective relief of reduced motility caused by opioid therapy. - Bowel preparation for diagnostic procedures: can be incorporated into a cleansing regimen prior to colonoscopy or similar examinations.

What are the side effects of Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Laxido may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating - Flatulence - Nausea - Abdominal cramps - Diarrhoea - Headache

Serious or Rare Side Effects: - Severe electrolyte imbalance (hyper‑ or hyponatraemia, hyperkalaemia) - Allergic reaction (rash, itching, swelling) - Dehydration - Renal impairment in susceptible patients - Severe abdominal pain - Anaphylaxis

What precautions apply to Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

When using Laxido, consider the following safety measures. - Assess renal function: patients with impaired kidneys may accumulate electrolytes. - Monitor electrolytes: especially sodium and potassium during prolonged therapy. - Avoid in intestinal obstruction: risk of perforation or worsening blockage. - Use caution in elderly: increased susceptibility to dehydration and electrolyte shifts. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 interact with?

Laxido can interact with other medicines that affect electrolyte balance or renal function.

Major Interactions (Avoid): - Concurrent high‑dose potassium supplements: risk of hyperkalaemia. - Loop diuretics: may increase electrolyte loss. - Other osmotic laxatives: additive effect causing severe diarrhoea.

Moderate Interactions (Monitor Closely): - ACE inhibitors: monitor serum potassium levels. - NSAIDs: watch renal function during combined use.

Frequently asked questions

What is Laxido used for?+
Laxido is an oral osmotic laxative indicated for the relief of chronic constipation and for bowel cleansing before diagnostic procedures such as colonoscopy. It works by drawing water into the intestines, softening stool and promoting regular bowel movements.
How does the active ingredient in Laxido work?+
The primary active component, macrogol 3350, is a large, non‑absorbable polymer that creates an osmotic gradient, retaining water in the intestinal lumen. The accompanying electrolytes help maintain fluid balance while the increased water content softens stool and stimulates peristalsis.
What is the usual dose of Laxido?+
The dose of Laxido is individualized by the prescribing healthcare professional based on the patient’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and the product label for preparation and administration.
Is Laxido safe to use during pregnancy or breastfeeding?+
Safety data for Laxido in pregnancy and lactation are limited. It should only be used if clearly needed and after a risk‑benefit assessment by a qualified healthcare provider. Women who are pregnant or breastfeeding should discuss alternatives with their doctor.
How do I order Laxido from GNH USA?+
To place an order, submit an enquiry on the Laxido product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Laxido compare with other laxatives?+
Laxido, containing macrogol 3350, is an osmotic laxative that generally provides a gentler, more predictable effect compared with stimulant laxatives such as bisacodyl. It is less likely to cause cramping and is suitable for long‑term use, whereas stimulant agents act quickly but may lead to dependence.
What are the storage and handling requirements for Laxido?+
Laxido should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture. Keep the product away from direct sunlight and out of reach of children.
How is Laxido administered?+
Laxido is supplied as a powder that is dissolved in water according to the instructions on the label. The solution is taken orally, usually once daily, or as directed by a healthcare professional for bowel preparation protocols.
What are the most serious risks associated with Laxido?+
Serious risks include severe electrolyte disturbances such as hyperkalaemia or hyponatraemia, dehydration, and rare allergic reactions that may present as rash, swelling or anaphylaxis. Patients with renal impairment or intestinal obstruction should be monitored closely.
Who should not use Laxido?+
Laxido is contraindicated in patients with known hypersensitivity to any component, in those with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in individuals with significant renal failure unless closely supervised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Route
Oral Use
Manufacturer
Intergal Pharma Ireland Limited
Origin
EU

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