GNH USA

Europe — EMA

Laxido Orange

GNH USA supplies Laxido Orange (Macrogol 3350), an osmotic laxative for constipation and occasional bowel irregularity. Request a quote for global supply.

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

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What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol 3350, the active ingredient in Laxido Orange, is an osmotic laxative presented as an oral solution for oral administration. It works by retaining water in the intestinal lumen, thereby softening stool and promoting regular bowel movements. The product is used to alleviate constipation and occasional bowel irregularity in adults and, when prescribed, in pediatric patients.

GNH USA supplies Laxido Orange as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for this European‑market osmotic laxative.

What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 used for?

Laxido Orange, an osmotic laxative, is employed to manage conditions affecting bowel transit and stool consistency.

- Constipation: softens stool and facilitates regular bowel movements in individuals with infrequent or difficult evacuation. - Occasional bowel irregularity: provides temporary relief for sporadic irregularity without chronic use. - Functional constipation: improves stool frequency and consistency in functional bowel disorders.

What are the side effects of Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Laxido Orange may be associated with a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating: sensation of fullness or swelling in the abdomen. - Flatulence: increased intestinal gas production. - Diarrhoea: loose, watery stools occurring more frequently. - Nausea: mild feeling of queasiness.

Serious or Rare Side Effects: - Severe dehydration: marked loss of body fluids requiring medical attention. - Electrolyte imbalance: abnormal levels of sodium, potassium or chloride that may cause cardiac or neurological symptoms.

What precautions apply to Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

When using Laxido Orange, certain precautions should be observed to ensure safe and effective therapy. - Assess renal function: patients with impaired kidney function may require monitoring of fluid and electrolyte status. - Evaluate electrolyte balance: individuals on diuretic therapy or with existing electrolyte disorders should be reviewed before initiation. - Limit duration of use: avoid prolonged continuous use without medical supervision to prevent dependence. - Monitor for abdominal pain: persistent or severe abdominal discomfort warrants clinical assessment. - Store at ambient temperature: keep below 25°C, retain in original container, protect from moisture and direct sunlight.

What does Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 interact with?

Laxido Orange can interact with other medicines, influencing their absorption or electrolyte balance.

Major Interactions (Avoid): - Digoxin: increased risk of toxicity due to electrolyte shifts, especially potassium loss. - Lithium: enhanced lithium reabsorption may raise serum levels and precipitate toxicity.

Moderate Interactions (Monitor Closely): - Antacids containing aluminium or magnesium: may reduce the laxative’s efficacy by binding. - Oral antibiotics (e.g., tetracyclines): concurrent use may diminish antibiotic absorption. - Diuretics: combined effect on fluid and electrolyte balance may require dose adjustment.

Frequently asked questions

What is Laxido Orange used for?+
Laxido Orange is an oral osmotic laxative indicated for the relief of constipation and occasional bowel irregularity. It works by increasing water content in the stool, making bowel movements easier and more regular for adults and, when prescribed, for appropriate pediatric patients.
How does Macrogol 3350 work?+
Macrogol 3350 is a high‑molecular‑weight polymer that remains largely unabsorbed in the gut. It creates an osmotic gradient that draws water into the intestinal lumen, softening stool and expanding its volume, which stimulates peristalsis and promotes more frequent, softer bowel movements.
What is the usual dose of Laxido Orange?+
The dose of Laxido Orange is individualized by a healthcare professional based on the patient’s age, weight, severity of constipation and clinical response. Prescribers determine the appropriate volume and frequency, and patients should follow the specific instructions provided by their clinician.
Is Laxido Orange safe during pregnancy or breastfeeding?+
Safety data for Macrogol 3350 during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after evaluating the clinical situation.
How do I order Laxido Orange from GNH USA?+
To order Laxido Orange, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Laxido Orange compare with other laxatives?+
Compared with stimulant laxatives, Laxido Orange works by osmotic water retention rather than stimulating intestinal muscle activity, resulting in a gentler, more physiologic softening of stool. It is generally preferred for short‑term use and for patients who need a predictable, electrolyte‑balanced formulation.
How should Laxido Orange be stored and handled?+
Laxido Orange should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in its original packaging until use to maintain product stability.
How is Laxido Orange administered?+
Laxido Orange is taken orally as a measured dose of the liquid solution. The prescribed volume is usually mixed with a small amount of water or juice, if desired, and consumed according to the healthcare professional’s instructions, typically on an empty stomach for optimal effect.
What are the most serious risks to watch for with Laxido Orange?+
The most serious risks include severe dehydration and electrolyte disturbances, particularly low potassium or sodium levels, which can lead to cardiac arrhythmias or neurological symptoms. Patients experiencing persistent diarrhoea, dizziness, muscle weakness or abnormal heart rhythm should seek medical attention promptly.
Who should not use Laxido Orange?+
Laxido Orange should be avoided in individuals with known hypersensitivity to macrogol or any of its excipients, in patients with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in those with uncontrolled electrolyte imbalances unless closely monitored by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Route
Oral Use
Manufacturer
Intergal Pharma Ireland Limited
Origin
EU

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