GNH USA

Europe — EMA

Lattulosio Zentiva

GNH USA supplies Lattulosio Zentiva (Lactulose), an osmotic laxative for constipation and hepatic encephalopathy.

Lactulose

Request sourcing

1
Pack/s

What is Lactulose?

Lactulose, the active ingredient in Lattulosio Zentiva, is an osmotic laxative presented as an oral solution for oral use. It is employed to relieve constipation and to manage hepatic encephalopathy by lowering blood ammonia levels in patients with liver disease.

GNH USA supplies Lattulosio Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Lactulose used for?

Lattulosio Zentiva is an osmotic laxative that acts on the gastrointestinal tract to treat the following conditions: - Constipation: softens stools and promotes regular bowel movements. - Hepatic encephalopathy: reduces intestinal ammonia production, helping improve mental status in patients with liver dysfunction.

What are the side effects of Lactulose?

Lactulose may cause a range of adverse reactions. Monitoring patients for any new symptoms is recommended.

Common Side Effects: - Abdominal bloating: feeling of fullness or swelling in the abdomen. - Flatulence: increased intestinal gas. - Diarrhea: loose, watery stools. - Nausea: sensation of unease or urge to vomit. - Stomach cramps: intermittent abdominal pain. - Thirst: increased desire for fluids.

Serious or Rare Side Effects: - Severe electrolyte imbalance: abnormal levels of sodium, potassium, or other electrolytes. - Dehydration: excessive loss of body fluids. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Hepatic decompensation: worsening liver function in susceptible patients. - Persistent vomiting: inability to retain oral intake.

What precautions apply to Lactulose?

Before initiating therapy with Lattulosio Zentiva, consider the following safety measures: - Renal impairment: use with caution and monitor renal function. - Diabetes mellitus: monitor blood glucose as lactulose may affect carbohydrate metabolism. - Pediatric use: dosage must be individualized and supervised by a pediatric specialist. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Lactulose interact with?

Lactulose can interact with other medicines, requiring attention to avoid reduced efficacy or increased adverse effects.

Major Interactions (Avoid): - Magnesium‑containing antacids: may enhance the laxative effect, leading to excessive diarrhea. - High‑dose insulin or oral hypoglycemics: may increase risk of hypoglycemia due to altered carbohydrate absorption.

Moderate Interactions (Monitor Closely): - Diuretics: monitor electrolytes for potential imbalance. - Mineral supplements (e.g., calcium, iron): may cause gastrointestinal discomfort. - Antibiotics: may alter gut flora, potentially affecting lactulose metabolism.

Frequently asked questions

What is Lattulosio Zentiva used for?+
Lattulosio Zentiva contains lactulose, which is prescribed to treat constipation by softening stools and to manage hepatic encephalopathy by lowering ammonia levels in the gut, thereby improving neurological symptoms in patients with liver disease.
How does lactulose work?+
Lactulose reaches the colon unchanged, where bacterial enzymes split it into short‑chain fatty acids. This creates an osmotic gradient that draws water into the intestinal lumen, softening stool, and the resulting acidic environment converts ammonia to ammonium, reducing its absorption into the bloodstream.
What is the usual dose of Lattulosio Zentiva?+
The appropriate dose of lactulose is determined by the prescribing clinician based on the patient’s condition, age, renal function, and response to therapy. Dosage may be adjusted during treatment to achieve the desired clinical effect.
Is lactulose safe during pregnancy or breastfeeding?+
Lactulose is classified as a Category B medication in many jurisdictions, indicating no proven risk in animal studies but limited human data. Healthcare providers should evaluate the risk‑benefit ratio before prescribing it to pregnant or nursing women.
How do I order Lattulosio Zentiva from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does lactulose compare with other laxatives?+
Unlike stimulant laxatives that trigger intestinal motility, lactulose works osmotically, drawing water into the colon and softening stool. It also has the unique benefit of reducing ammonia absorption, making it the preferred choice for patients with hepatic encephalopathy, whereas stimulant agents lack this effect.
How should Lattulosio Zentiva be stored?+
Store the product at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging to maintain stability.
How is Lattulosio Zentiva administered?+
Lattulosio Zentiva is taken orally, usually as a liquid solution. It can be measured with a calibrated dosing device and mixed with water or another non‑carbonated beverage if preferred. Administration should follow the prescriber’s instructions regarding timing and volume.
What are the most serious risks associated with lactulose?+
Serious adverse events include severe electrolyte disturbances, marked dehydration, and rare allergic reactions such as rash or difficulty breathing. Patients with advanced liver disease should be monitored for signs of hepatic decompensation while on therapy.
Who should not use lactulose?+
Lactulose is contraindicated in individuals with known hypersensitivity to lactulose or any component of the formulation. Caution is advised for patients with severe renal impairment, intestinal obstruction, or active gastrointestinal bleeding, and it should be avoided unless directed by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Lactulose
Route
Oral Use
Manufacturer
Zentiva Italia S.R.L.
Origin
EU

Related products