Lattulosio Almus

Lactulose, the active ingredient in Lattulosio Almus, is an osmotic laxative presented as an oral preparation for oral use. It is indicated for the relief of constipation and for the management of hepatic encephalopathy in adult patients.

GNH USA supplies Lattulosio Almus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for global distribution, ensuring product integrity from manufacturing to end‑user.

Lactulose is used as an osmotic laxative and ammonia‑lowering agent in specific gastrointestinal and hepatic conditions. - Constipation: Relieves chronic constipation by increasing stool water content and promoting bowel movements. - Hepatic encephalopathy: Reduces blood ammonia levels, helping to prevent or treat episodes of hepatic encephalopathy. - Pre‑procedure bowel cleansing: Facilitates colonic evacuation before diagnostic or therapeutic procedures.

Lactulose may cause a range of adverse reactions, most of which are related to its osmotic activity in the gut.

Common Side Effects: - Abdominal cramping - Flatulence - Diarrhea - Nausea

Serious or Rare Side Effects: - Severe electrolyte imbalance (e.g., hyponatremia, hypokalemia) - Marked dehydration - Allergic reactions such as rash or angioedema - Hepatic decompensation in advanced liver disease

When prescribing lactulose, consider several safety measures to minimise risk. - Renal function assessment: Evaluate kidney function before initiating therapy, especially in patients with chronic kidney disease. - Electrolyte monitoring: Check serum electrolytes periodically during prolonged use. - Diabetes caution: Monitor blood glucose as lactulose may affect carbohydrate metabolism. - Intestinal obstruction: Avoid use in patients with known bowel obstruction or perforation. - Store at room temperature: Keep in the original container, protect from moisture and direct sunlight.

Lactulose can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Concurrent use with other osmotic laxatives: May cause severe diarrhea and fluid loss. - Combination with potent diuretics: Increases risk of electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Mineral supplements (e.g., calcium, magnesium): May reduce lactulose efficacy by binding in the gut. - Antibiotics altering gut flora: May affect lactulose metabolism and ammonia reduction. - Probiotic products: Potentially modify intestinal fermentation, influencing therapeutic effect.