GNH USA

Europe — EMA

Latanoprost/Timolol Zentiva

GNH USA supplies Latanoprost/Timolol Zentiva (Timolol/Latanoprost), a prostaglandin analog/beta blocker for open-angle glaucoma and ocular hypertension.

Timolol Maleate, Latanoprost

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What is Timolol Maleate, Latanoprost?

Timolol maleate and Latanoprost, the active ingredients in Latanoprost/Timolol Zentiva, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They treat open‑angle glaucoma and ocular hypertension in adult patients.

GNH USA supplies Latanoprost/Timolol Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol Maleate, Latanoprost used for?

Latanoprost/Timolol Zentiva is indicated for conditions affecting intra‑ocular pressure within the glaucoma disease family.

Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic‑nerve damage. Ocular hypertension: reduces pressure to lower the risk of progression to glaucoma. Secondary glaucoma: assists in pressure control when other therapies are insufficient.

What are the side effects of Timolol Maleate, Latanoprost?

Common Side Effects: - Eye irritation or burning sensation. - Blurred vision shortly after instillation. - Conjunctival hyperemia (eye redness). - Itching or mild allergic reaction on the eyelid. - Dry eye or foreign‑body sensation. - Increased pigmentation of the iris.

Serious or Rare Side Effects: - Severe allergic reaction (angio‑edema, anaphylaxis). - Worsening of glaucoma or sudden loss of pressure control. - Chest pain or symptomatic bradycardia. - Bronchospasm in patients with asthma/COPD. - Persistent eye pain or vision loss. - Corneal ulceration or infection.

What precautions apply to Timolol Maleate, Latanoprost?

Before using Latanoprost/Timolol Zentiva, consider the following precautions.

Assess cardiovascular status: avoid in patients with severe bradycardia or heart block. Check respiratory history: contraindicated in active asthma or severe COPD. Monitor intra‑ocular pressure: ensure adequate pressure reduction after initiation. Avoid concurrent beta‑blocker eye drops: may cause additive hypotensive effect. Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment. Store at room temperature: keep in the original container, protect from light and moisture.

What does Timolol Maleate, Latanoprost interact with?

Latanoprost/Timolol Zentiva may interact with other medicines.

Major Interactions (Avoid): - Systemic non‑selective beta‑blockers: additive bradycardia risk. - Calcium channel blockers: may enhance ocular hypotensive effect. - Other prostaglandin analog eye drops: increase risk of ocular side effects.

Moderate Interactions (Monitor Closely): - Anticholinergic ophthalmic agents: may affect pupil response. - Systemic antihypertensives: monitor blood pressure for excessive lowering. - Inhaled beta‑agonists: may reduce bronchodilator efficacy.

Frequently asked questions

What is Latanoprost/Timolol Zentiva used for?+
Latanoprost/Timolol Zentiva is a prescription ophthalmic solution used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic‑nerve damage and preserve visual function.
How does the combination of Timolol and Latanoprost work?+
Latanoprost increases the outflow of aqueous humor through the uveoscleral pathway, while Timolol reduces the production of aqueous humor by blocking beta‑adrenergic receptors in the ciliary body. Together they provide a complementary reduction in eye pressure.
What is the usual dose of Latanoprost/Timolol Zentiva?+
The dosing regimen is determined by the prescribing ophthalmologist based on the patient’s condition, response, and tolerance. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the prescriber’s instructions.
Is Latanoprost/Timolol Zentiva safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. The product should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.
How do I order Latanoprost/Timolol Zentiva from GNH USA?+
Enquiries are submitted via the product page on gnh-usa.com, where you specify the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Latanoprost/Timolol compare with other glaucoma treatments?+
Compared with monotherapy agents, the combination offers dual mechanisms—enhanced outflow and reduced production—often achieving greater pressure reduction with a single drop. It may be preferred when single‑agent therapy does not reach target pressure, but individual response and tolerance vary.
What are the storage and handling requirements for Latanoprost/Timolol Zentiva?+
Store the eye‑drop bottle at room temperature, away from direct sunlight and moisture. Keep it in the original packaging until use, and discard any remaining solution after the indicated period after opening, typically 30 days, as advised by the label.
How is Latanoprost/Timolol Zentiva administered?+
The solution is applied as a single drop into the conjunctival sac of each affected eye, usually in the evening. The patient should avoid touching the tip of the bottle to the eye or any surface to maintain sterility.
What are the most serious risks associated with Latanoprost/Timolol Zentiva?+
Serious risks include severe allergic reactions, marked reduction in intra‑ocular pressure leading to hypotony, bronchospasm in susceptible individuals, and systemic cardiovascular effects such as bradycardia or chest pain. Patients should seek immediate medical attention if these occur.
Who should not use Latanoprost/Timolol Zentiva?+
The product is contraindicated in patients with known hypersensitivity to either component, severe bronchial asthma, chronic obstructive pulmonary disease, sinus bradycardia, second‑ or third‑degree heart block, or in those using non‑selective systemic beta‑blockers without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Timolol Maleate, Latanoprost
Route
Ocular Use
Manufacturer
Zentiva, K.S.
Origin
EU

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