GNH USA

Europe — EMA

Latanoprost/Timolol Olikla

GNH USA supplies Latanoprost/Timolol Olikla (Timolol Maleate and Latanoprost), a beta‑blocker and prostaglandin analog combination for open‑angle glaucoma

Timolol Maleate, Latanoprost

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What is Timolol Maleate, Latanoprost?

Timolol Maleate, the active ingredient in Latanoprost/Timolol Olikla, is a beta‑blocker and prostaglandin analog combination presented as an ophthalmic solution for ocular (topical) use. It treats open‑angle glaucoma and ocular hypertension in adults.

GNH USA supplies Latanoprost/Timolol Olikla as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol Maleate, Latanoprost used for?

Latanoprost/Timolol Olikla is used to manage intraocular pressure in glaucoma and ocular hypertension.

- Open‑angle glaucoma: reduces intraocular pressure to slow disease progression. - Ocular hypertension: lowers elevated eye pressure to prevent development of glaucoma. - Secondary open‑angle glaucoma: helps control pressure when other treatments are insufficient.

What are the side effects of Timolol Maleate, Latanoprost?

Latanoprost/Timolol Olikla may cause ocular and systemic adverse reactions.

Common Side Effects: - Eye irritation: transient burning or stinging after instillation. - Conjunctival hyperemia: mild redness of the eye. - Eyelash changes: increased length or thickness. - Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, rash, or difficulty breathing. - Persistent ocular inflammation: uveitis or keratitis. - Systemic bradycardia: markedly reduced heart rate.

What precautions apply to Timolol Maleate, Latanoprost?

When using Latanoprost/Timolol Olikla, consider the following precautions.

- Contraindicated in patients with known hypersensitivity to beta‑blockers or prostaglandin analogues: avoid use. - Caution in patients with asthma, chronic obstructive pulmonary disease, or severe cardiac disease: monitor respiratory and cardiac status. - Use with care in patients with narrow-angle glaucoma: may precipitate angle closure. - Avoid concurrent use with other ocular beta‑blocker or prostaglandin products: risk of additive effects. - Discontinue if severe ocular irritation or allergic reaction occurs: seek medical advice. - Store at room temperature (below 25 °C): keep in original container, protect from light and moisture.

What does Timolol Maleate, Latanoprost interact with?

Latanoprost/Timolol Olikla can interact with several systemic and ocular agents.

Major Interactions (Avoid): - Systemic non‑selective beta‑blockers (e.g., propranolol): additive bradycardia or hypotension. - MAO inhibitors or other drugs affecting adrenergic tone: risk of severe cardiovascular effects. - Other prostaglandin analogues (e.g., bimatoprost): increased risk of ocular side effects.

Moderate Interactions (Monitor Closely): - Anticholinergic agents: may reduce ocular surface lubrication, increasing irritation. - Carbonic anhydrase inhibitors (e.g., dorzolamide): potential additive intraocular pressure lowering. - Sympathomimetic eye drops (e.g., phenylephrine): may counteract beta‑blocker effect.

Frequently asked questions

What is Latanoprost/Timolol Olikla used for?+
Latanoprost/Timolol Olikla is a prescription ophthalmic solution indicated for the reduction of intraocular pressure in patients with open‑angle glaucoma and ocular hypertension. By lowering eye pressure, it helps to prevent optic nerve damage and preserve visual function.
How does Timolol Maleate work in this combination?+
Timolol Maleate, a non‑selective beta‑adrenergic blocker, decreases the production of aqueous humor by inhibiting beta receptors in the ciliary body. This reduction in fluid formation contributes to lower intraocular pressure when combined with Latanoprost.
What is the usual dose of Latanoprost/Timolol Olikla?+
The specific dosing regimen is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency must be individualized based on the patient’s condition and response.
Is Latanoprost/Timolol Olikla safe during pregnancy or breastfeeding?+
Safety data for use in pregnancy or lactation are limited. The product should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision should be made in consultation with a healthcare professional.
How do I order Latanoprost/Timolol Olikla from GNH USA?+
To request Latanoprost/Timolol Olikla, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does this combination compare with using latanoprost alone?+
Latanoprost alone primarily increases uveoscleral outflow, while the combination adds timolol’s ability to reduce aqueous humor production. This dual mechanism often yields greater intraocular pressure reduction than latanoprost monotherapy, especially in patients who need additional pressure control.
How should Latanoprost/Timolol Olikla be stored and handled?+
Store the ophthalmic solution at room temperature, preferably below 25 °C, in its original container. Protect it from light and moisture, and keep the bottle tightly closed when not in use to maintain sterility and potency.
How is Latanoprost/Timolol Olikla administered?+
The eye drops are applied topically to the conjunctival sac. Tilt the head back, pull down the lower eyelid to create a small pocket, and place one drop into the pocket. Close the eye gently and avoid blinking excessively for a few seconds to allow absorption.
What are the most serious risks associated with Latanoprost/Timolol Olikla?+
Serious adverse events include severe allergic reactions (e.g., swelling, rash, breathing difficulty), persistent ocular inflammation such as uveitis or keratitis, and systemic bradycardia that may cause faintness or low blood pressure. Immediate medical attention is required if any of these occur.
Who should not use Latanoprost/Timolol Olikla?+
The product is contraindicated in individuals with known hypersensitivity to either timolol, latanoprost, or any component of the formulation. It should also be avoided in patients with severe asthma, chronic obstructive pulmonary disease, advanced heart block, or uncontrolled cardiac disease without careful medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol Maleate, Latanoprost
Route
Ocular Use
Manufacturer
Olikla S.R.O.
Origin
EU

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