GNH USA

Europe — EMA

Lastin

GNH USA supplies Lastin (Azelastine Hydrochloride), an antihistamine for allergic rhinitis and hay fever. Request a quote for global supply.

Azelastine Hydrochloride

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What is Azelastine Hydrochloride?

Azelastine Hydrochloride, the active ingredient in Lastin, is an antihistamine presented as a nasal spray for nasal use. It treats allergic rhinitis (seasonal and perennial) and hay fever in adults and children.

GNH USA supplies Lastin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Azelastine Hydrochloride used for?

Lastin, an antihistamine nasal spray, acts on the histamine pathway to relieve symptoms of allergic airway disease.

Allergic rhinitis (seasonal): reduces nasal congestion, itching, sneezing and rhinorrhea. Allergic rhinitis (perennial): provides consistent relief of chronic nasal allergy symptoms. Hay fever: alleviates typical hay‑fever nasal complaints such as watery eyes and runny nose.

What are the side effects of Azelastine Hydrochloride?

Common Side Effects: - Nasal irritation or burning sensation. - Bitter taste after administration. - Headache. - Drowsiness or mild fatigue. - Throat irritation. - Sneezing.

Serious or Rare Side Effects: - Epistaxis (nosebleed). - Severe allergic reaction such as anaphylaxis. - Nasal ulceration or crusting. - Vision changes or ocular irritation.

What precautions apply to Azelastine Hydrochloride?

Before using Lastin, consider the following precautions.

Pregnancy: consult a healthcare professional as safety data are limited. Breastfeeding: use with caution; limited information is available. Concomitant CNS depressants: may increase drowsiness. Use in children: follow pediatric dosing guidance. Avoid spray into eyes: may cause irritation. Store at room temperature: keep in the original container, protect from moisture and heat.

What does Azelastine Hydrochloride interact with?

Azelastine may interact with other substances; monitor the following.

Major Interactions (Avoid): - Alcohol: additive sedative effect. - Other antihistamines: risk of excessive anticholinergic load.

Moderate Interactions (Monitor Closely): - CYP450 inhibitors or inducers: may alter azelastine metabolism. - Beta‑blockers: may mask symptoms of severe allergic reactions. - Nasal decongestants: may increase local irritation when used together.

Frequently asked questions

What is Lastin used for?+
Lastin is an over‑the‑counter nasal spray containing azelastine hydrochloride. It is indicated for the relief of symptoms associated with allergic rhinitis, including seasonal and perennial forms, as well as hay fever. The spray helps reduce nasal congestion, itching, sneezing, and runny nose.
How does azelastine hydrochloride work?+
Azelastine hydrochloride works by selectively blocking H1‑histamine receptors in the nasal mucosa, preventing histamine‑mediated inflammation and sensory nerve activation. This antagonism reduces vasodilation, vascular permeability, and the release of inflammatory mediators, leading to decreased nasal swelling and irritation.
What is the usual dose of Lastin?+
The dosing regimen for Lastin is determined by a qualified prescriber based on the patient’s age, severity of symptoms, and clinical response. Typically, one or two sprays per nostril are used, but the exact number and frequency should follow the healthcare professional’s instructions.
Is Lastin safe during pregnancy or breastfeeding?+
Safety data for azelastine hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lastin.
How do I order Lastin from GNH USA?+
To order Lastin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Lastin compare with other antihistamine nasal sprays?+
Lastin contains azelastine, a second‑generation antihistamine with both antihistaminic and anti‑inflammatory properties. Compared with first‑generation sprays, azelastine generally causes less sedation. Its rapid onset and dual action often provide quicker symptom relief than some older agents, while maintaining a favorable safety profile.
How should Lastin be stored and handled?+
Lastin should be stored at room temperature, away from direct sunlight and excessive heat. Keep the spray in its original packaging to protect it from moisture. Do not freeze the product, and ensure the nozzle is clean and free of debris before each use.
How is Lastin administered?+
Lastin is administered as a nasal spray. The user gently inserts the tip into one nostril, closes the opposite nostril, and sprays the prescribed number of actuations while breathing in gently. The process is repeated in the other nostril if required, following the prescriber’s directions.
What are the most serious risks to watch for with Lastin?+
While most users experience only mild side effects, serious risks include nosebleeds (epistaxis), severe allergic reactions such as anaphylaxis, and nasal ulceration or crusting. If any of these occur, discontinue use immediately and seek medical attention.
Who should not use Lastin?+
Individuals with known hypersensitivity to azelastine hydrochloride or any component of the spray should avoid using Lastin. Patients with severe nasal obstruction, recent nasal surgery, or those taking monoamine oxidase inhibitors should consult a healthcare professional before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Azelastine Hydrochloride
Route
Nasal Use
Manufacturer
Viatris Aps
Origin
EU

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