Lastin

Azelastine, the active ingredient in Lastin, is an antihistamine presented as a nasal spray for intranasal use. It blocks histamine H1 receptors to relieve symptoms of allergic rhinitis, such as sneezing, itching, and nasal congestion, in adults and children.

GNH USA supplies Lastin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Our distribution network ensures timely delivery and reliable product traceability across multiple continents.

Azelastine nasal spray is used to treat allergic rhinitis by antagonizing H1 receptors in the nasal mucosa. - Seasonal allergic rhinitis: Reduces sneezing, itching, and nasal discharge. - Perennial allergic rhinitis: Improves nasal congestion and runny nose. - Non‑allergic rhinitis: Provides symptomatic relief of nasal irritation. - Hay fever: Alleviates typical allergy symptoms during pollen seasons. - Vasomotor rhinitis: Decreases nasal hyperreactivity and congestion. - Post‑operative nasal inflammation: Helps reduce swelling and irritation after nasal surgery.

Azelastine nasal spray may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Nasal irritation or burning sensation. - Sneezing. - Headache. - Bitter taste. - Dry nose. - Cough.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis). - Throat swelling. - Persistent nasal bleeding. - Vision changes. - Hallucinations or mood alterations.

When using Azelastine nasal spray, consider the following precautions to ensure safe and effective therapy. - Pregnancy: Consult a healthcare professional before use, as safety data are limited. - Breastfeeding: Discuss potential risks with a physician, as drug may be excreted in milk. - Age restrictions: Use in children only as directed by a prescriber. - Concomitant sedatives: Monitor for increased drowsiness when combined with CNS depressants. - Pre‑existing nasal conditions: Avoid use if nasal ulceration or severe infection is present. - Store at below 25°C: Keep in the original container, protect from moisture and heat.

Azelastine may interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic exposure. - Monoamine oxidase inhibitors (MAOIs): risk of additive antihistaminic effects.

Moderate Interactions (Monitor Closely): - Alcohol or CNS depressants: may enhance drowsiness or sedation. - Other antihistamines: combined use can increase sedation. - Nasal decongestant sprays: concurrent use may cause nasal irritation. - Anticholinergic agents: may exacerbate dry nasal mucosa.