Lapio Duo

Timolol Maleate and Latanoprost, the active ingredients in Lapio Duo, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They lower intra‑ocular pressure in patients with primary open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and visual field loss.

GNH USA supplies Lapio Duo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for export to multiple regions.

Lapio Duo is indicated for ocular conditions where reduction of intra‑ocular pressure is required.

Primary open‑angle glaucoma: reduces intra‑ocular pressure to prevent optic nerve damage and visual field loss. Ocular hypertension: lowers intra‑ocular pressure to reduce the risk of progression to glaucoma. Post‑operative ocular pressure spikes: helps control transient pressure elevation after eye surgery.

Common Side Effects: - Blurred vision - Eye irritation or burning sensation - Conjunctival hyperemia (redness) - Increased eyelash growth - Dry eye sensation - Mild pruritus

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angio‑edema, anaphylaxis) - Persistent eye pain or photophobia - Corneal edema or ulceration - Sudden loss of vision - Intra‑ocular inflammation - Systemic bradycardia or hypotension

Before initiating therapy, evaluate patient medical history and concomitant medications. - Cardiovascular assessment: monitor patients with bradycardia, heart block, or heart failure. - Respiratory caution: avoid in patients with asthma or chronic obstructive pulmonary disease. - Pregnancy and lactation: use only if potential benefit justifies potential risk. - Ocular surgery: discontinue prior to intra‑ocular procedures to reduce risk of delayed wound healing. - Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Major Interactions (Avoid): - Systemic beta‑blockers: may cause additive bradycardia or hypotension. - Other prostaglandin analog eye drops: may increase risk of ocular inflammation. - Sympathomimetic agents: can reduce the ocular hypotensive effect of timolol.

Moderate Interactions (Monitor Closely):\n- Carbonic anhydrase inhibitors: may produce excessive intra‑ocular pressure reduction. - Anticholinergic eye drops: may diminish the efficacy of timolol. - Non‑steroidal anti‑inflammatory eye drops: monitor for increased ocular irritation.