Lanzol

Lansoprazole, the active ingredient in Lanzol, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid secretion and is used to treat acid‑related disorders such as gastro‑oesophageal reflux disease and peptic ulcer disease.

GNH USA supplies Lanzol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lanzol (lansoprazole) acts on the gastric proton pump to manage several acid‑related conditions. - Gastro‑oesophageal reflux disease (GERD): relieves heartburn and esophageal irritation. - Peptic ulcer disease: promotes healing of gastric and duodenal ulcers. - NSAID‑induced ulcer prophylaxis: prevents ulcer formation in patients taking non‑steroidal anti‑inflammatory drugs. - Helicobacter pylori eradication (in combination therapy): enhances bacterial clearance when used with antibiotics. - Zollinger‑Ellison syndrome: controls excessive gastric acid production.

Adverse reactions may occur with lansoprazole therapy.

Common Side Effects: - Headache: mild to moderate intensity. - Diarrhoea: watery stools, usually transient. - Nausea: occasional upset stomach. - Abdominal pain: cramping or discomfort. - Flatulence: increased gas. - Constipation: reduced bowel movements.

Serious or Rare Side Effects: - Clostridioides difficile infection: severe colitis. - Severe allergic reactions: rash, angioedema, anaphylaxis. - Stevens‑Johnson syndrome/toxic epidermal necrolysis: skin blistering. - Liver enzyme elevation: hepatitis signs. - Hypomagnesemia: low serum magnesium. - Bone fracture risk: long‑term use may affect bone density.

Before initiating therapy, consider the following precautions. - Assess renal and hepatic function: adjust use if impairment exists. - Monitor for infections: especially C. difficile. - Evaluate need for long‑term therapy: reassess periodically. - Use caution in patients with osteoporosis: consider bone health. - Avoid abrupt discontinuation: may cause rebound acid hypersecretion. - Store at room temperature: keep in the original pack, protect from moisture.

Lansoprazole may interact with several medications.

Major Interactions (Avoid): - Atazanavir, nelfinavir, ketoconazole: reduced absorption and efficacy. - Clopidogrel: decreased activation, reduced antiplatelet effect. - Warfarin: possible increase in INR, enhanced anticoagulation.

Moderate Interactions (Monitor Closely): - Digoxin: increased serum levels, monitor cardiac function. - Methotrexate: reduced clearance, watch for toxicity. - HIV protease inhibitors: altered plasma concentrations, adjust dosing. - Vitamin B12: long‑term use may impair absorption, monitor levels.