Lanoxin Md

Digoxin, the active ingredient in Lanoxin Md, is a cardiac glycoside presented as an unspecified strength/oral tablet for oral use. It is used to improve cardiac contractility in heart failure and to control ventricular rate in atrial fibrillation.

GNH USA supplies Lanoxin Md as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Digoxin acts on the cardiac conduction system and myocardial contractility, making it valuable in several cardiovascular conditions.

- Heart failure: enhances myocardial contractility and reduces symptoms of congestion. - Atrial fibrillation: slows ventricular response to improve rate control. - Cardiac arrhythmias: provides rate control in certain supraventricular tachyarrhythmias.

Adverse reactions to digoxin can vary in frequency and severity.

Common Side Effects: - Nausea or vomiting - Diarrhea - Fatigue or weakness - Blurred vision or color disturbances - Headache - Dizziness

Serious or Rare Side Effects: - Cardiac arrhythmias (including ventricular tachycardia) - Severe bradycardia or heart block - Hyperkalemia - Allergic skin reactions - Visual disturbances such as yellow‑green halos - Confusion or hallucinations

When prescribing digoxin, clinicians should consider several safety factors.

- Renal impairment: adjust dose and monitor serum digoxin levels. - Electrolyte imbalance: correct potassium and magnesium abnormalities before initiation. - Thyroid disease: use with caution as hypothyroidism may increase sensitivity. - Elderly patients: start with lower doses due to increased susceptibility to toxicity. - Concomitant medications: review for potential interactions that may raise digoxin concentrations. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Digoxin has notable interactions that require careful management.

Major Interactions (Avoid): - Amiodarone: markedly increases digoxin plasma concentrations. - Quinidine: raises digoxin levels and may precipitate toxicity. - Verapamil: enhances digoxin exposure and can lead to bradyarrhythmias.

Moderate Interactions (Monitor Closely): - Loop and thiazide diuretics: may cause hypokalemia, increasing digoxin toxicity risk. - Beta‑blockers: additive effects on AV‑node conduction. - Macrolide antibiotics (e.g., erythromycin, clarithromycin): can elevate digoxin levels.