Lanoxin Injectie

Digoxin, the active ingredient in Lanoxin Injectie, is a cardiac glycoside presented as an injectable solution for intravenous use. It is employed in the management of heart failure and atrial fibrillation, improving cardiac contractility and controlling ventricular rate in adult patients with these conditions.

GNH USA supplies Lanoxin Injectie as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved documentation for each shipment.

Digoxin is a cardiac glycoside used in the management of cardiac conditions that affect heart contractility and rhythm.

Heart failure: improves cardiac contractility and reduces symptoms of fatigue and dyspnea. Atrial fibrillation: slows ventricular response and may aid in rhythm control. Cardiac arrhythmias: provides rate control in certain supraventricular tachyarrhythmias.

Digoxin may cause a range of adverse reactions, varying from mild to potentially life‑threatening.

Common Side Effects: - Nausea - Vomiting - Diarrhea - Fatigue - Dizziness - Blurred vision (yellow/green halos)

Serious or Rare Side Effects: - Cardiac arrhythmias - Severe bradycardia - Heart block - Hyperkalemia - Visual disturbances (scotoma) - Allergic reactions (anaphylaxis)

When using digoxin, several safety considerations are essential.

Renal function: adjust use in patients with impaired renal clearance. Electrolyte balance: monitor potassium and magnesium levels closely. Thyroid disease: use cautiously in hyperthyroid patients. Concomitant drugs: avoid medications that markedly alter digoxin concentrations. Pregnancy: category C, weigh benefits against potential risks. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Digoxin interacts with a variety of medicines that can affect its plasma concentration or pharmacodynamic response.

Major Interactions (Avoid): - Amiodarone: markedly increases digoxin serum concentrations. - Quinidine: raises digoxin levels. - Verapamil: enhances digoxin effect and toxicity risk. - Spironolactone: may increase digoxin concentrations. - Macrolide antibiotics (e.g., erythromycin): elevate digoxin levels.

Moderate Interactions (Monitor Closely): - Diuretics (loop, thiazide): cause electrolyte shifts influencing digoxin toxicity. - Beta‑blockers: additive effect on heart rate. - ACE inhibitors: may alter renal function affecting digoxin clearance. - Antacids containing aluminum or magnesium: reduce digoxin absorption. - Antidepressants (SSRIs): potential modest increase in digoxin levels.