Lanoxin

Digoxin, the active ingredient in Lanoxin, is a cardiac glycoside presented as an oral tablet for oral use. It is used to treat heart failure and atrial fibrillation by improving cardiac contractility and controlling heart rate. GNH USA supplies Lanoxin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lanoxin (digoxin) acts on the cardiac conduction system and myocardial contractility to manage specific cardiovascular conditions. - Heart failure: improves cardiac output and reduces symptoms of congestion. - Atrial fibrillation: helps control ventricular rate and may restore sinus rhythm. - Atrial flutter: assists in controlling ventricular response during rapid atrial rates.

Adverse reactions to digoxin can vary in frequency and severity.

Common Side Effects: - Nausea or vomiting - Diarrhea - Loss of appetite - Fatigue - Blurred vision or color perception changes - Headache

Serious or Rare Side Effects: - Cardiac arrhythmias, including ventricular tachycardia - Severe bradycardia or heart block - Hyperkalemia - Visual disturbances such as yellow‑green halos - Allergic reactions, including rash or angioedema

When prescribing or dispensing digoxin, several safety considerations are essential. - Renal function monitoring: adjust dose in patients with impaired clearance. - Electrolyte balance: correct hypokalemia, hypomagnesemia, or hypercalcemia before therapy. - Serum digoxin level: periodic measurement to avoid toxicity. - Pregnancy: use only if benefits outweigh risks (Category C). - Concomitant cardiac conditions: avoid in patients with ventricular fibrillation. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Digoxin interacts with several medicines that can alter its plasma concentration or cardiac effects.

Major Interactions (Avoid): - Amiodarone: markedly increases digoxin levels. - Quinidine: raises digoxin concentrations and risk of toxicity. - Verapamil: enhances digoxin exposure and may precipitate arrhythmias.

Moderate Interactions (Monitor Closely): - Diuretics (especially thiazides): may cause electrolyte disturbances that predispose to toxicity. - ACE inhibitors: can increase serum digoxin by reducing renal clearance.