Lanoxin 125

Digoxin, the active ingredient in Lanoxin 125, is a cardiac glycoside presented as a 125 µg oral tablet. It is used to improve cardiac contractility and control heart rate in patients with heart failure and atrial fibrillation.\n\nGNH India supplies Lanoxin 125 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to this essential cardiac medication while adhering to stringent quality and regulatory standards.

Digoxin is employed in the management of cardiac conditions that involve reduced contractility or abnormal rhythm.\n\n- Heart failure: improves ventricular contractility and reduces symptoms of fluid overload.\n- Atrial fibrillation: slows atrioventricular node conduction to control ventricular rate.\n- Atrial flutter: helps regulate ventricular response during rapid atrial rates.

Common Side Effects:\n- Nausea: mild to moderate gastrointestinal upset.\n- Vomiting: occasional emesis, especially after dose initiation.\n- Diarrhea: loose stools may occur.\n- Fatigue: general tiredness or weakness.\n- Blurred vision: visual disturbances such as halos.\n- Dizziness: light‑headedness or vertigo.\n\nSerious or Rare Side Effects:\n- Cardiac arrhythmias: potentially life‑threatening rhythm disturbances.\n- Severe bradycardia: markedly slow heart rate requiring medical attention.\n- AV block: impaired atrioventricular conduction.\n- Hyperkalemia: elevated serum potassium levels.\n- Allergic reactions: rash, itching, or anaphylaxis.\n- Visual disturbances: yellow‑green color vision changes.

Digoxin requires careful monitoring in several clinical situations.\n\n- Renal impairment: adjust dose and monitor serum digoxin levels.\n- Electrolyte imbalance: correct potassium and magnesium before therapy.\n- Thyroid disease: use with caution due to altered metabolism.\n- Elderly patients: increased sensitivity; monitor for toxicity.\n- Drug interactions: review concomitant medications for potential effects.\n- Store at ambient temperature: keep below 25 °C, retain in original container, protect from moisture.

Digoxin interacts with many medicines that can alter its plasma concentration or cardiac effects.\n\nMajor Interactions (Avoid):\n- Amiodarone: increases digoxin levels, raising toxicity risk.\n- Quinidine: raises digoxin concentrations.\n- Verapamil: may cause bradycardia and elevated digoxin levels.\n- Spironolactone: potentiates digoxin effect.\n- Macrolide antibiotics (e.g., erythromycin): elevate digoxin levels.\n\nModerate Interactions (Monitor Closely):\n- Diuretics (loop or thiazide): cause electrolyte shifts affecting digoxin activity.\n- Beta‑blockers: additive effect on heart rate and conduction.\n- ACE inhibitors: may modestly increase digoxin concentrations.