Lannatam

Tamsulosin Hydrochloride, the active ingredient in Lannatam, is a Alpha-1 adrenergic antagonist presented as an oral tablet for oral use. It treats benign prostatic hyperplasia in adult men, improving urinary flow and reducing related symptoms.

GNH USA supplies Lannatam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lannatam (tamsulosin) belongs to the alpha‑1 adrenergic antagonist class and is used to manage conditions related to prostate enlargement.

- Benign prostatic hyperplasia: relieves urinary obstruction and improves flow rates. - Lower urinary tract symptoms due to BPH: reduces urgency, frequency and nocturia. - Urinary retention caused by BPH: facilitates bladder emptying and decreases the need for catheterisation.

Lannatam may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Dizziness: feeling light‑headed, especially when standing quickly. - Headache: mild to moderate intensity. - Abnormal ejaculation: reduced volume or retrograde flow. - Nasal congestion: stuffy or runny nose. - Orthostatic hypotension: drop in blood pressure upon standing.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure requiring medical attention. - Syncope: fainting episodes. - Priapism: prolonged, painful erection. - Allergic reactions: rash, itching, swelling or anaphylaxis. - Intra‑operative floppy iris syndrome: potential complication during eye surgery.

Before initiating therapy with Lannatam, certain safety considerations should be reviewed.

- Renal impairment: use with caution and monitor renal function. - Hepatic impairment: dose adjustment may be required in severe liver disease. - Hypotension: assess baseline blood pressure and monitor for orthostatic changes. - Surgery: inform the surgeon of tamsulosin use, especially for eye procedures. - Drug interactions: review concomitant medications for additive hypotensive effects. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and light.

Lannatam can interact with several medicines, influencing its safety and efficacy.

Major Interactions (Avoid): - Potent CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase tamsulosin plasma levels. - CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): can alter metabolism and raise exposure. - Other alpha‑blockers (e.g., prazosin): additive hypotensive effect.

Moderate Interactions (Monitor Closely):\n- Diuretics: heightened risk of orthostatic hypotension. - Antihypertensives (e.g., ACE inhibitors, ARBs): monitor blood pressure for excessive lowering. - Warfarin: occasional reports of altered INR; regular coagulation monitoring advised.