GNH USA

Europe — EMA

Lanitop

GNH USA supplies Lanitop (Metildigoxin), a cardiac glycoside for heart failure and atrial fibrillation. Request a quote for worldwide supply to hospitals.

Metildigoxin

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What is Metildigoxin?

Metildigoxin, the active ingredient in Lanitop, is a cardiac glycoside presented as an oral formulation for oral use. It is used to improve cardiac contractility in patients with heart failure and to control ventricular rate in atrial fibrillation. It is indicated for chronic management of symptomatic heart failure and for rate control in atrial fibrillation with rapid ventricular response.

GNH USA supplies Lanitop as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance. The product conforms to European Union pharmacopeial standards and is intended for prescription use by qualified healthcare professionals.

What is Metildigoxin used for?

Metildigoxin acts on the cardiac conduction system and myocardial contractility, making it useful in specific heart conditions.

- Heart failure: improves symptoms, functional capacity and reduces hospitalisation rates. - Atrial fibrillation with rapid ventricular response: helps control ventricular rate and stabilises rhythm. - Chronic systolic dysfunction: enhances cardiac output by increasing myocardial contractility.

What are the side effects of Metildigoxin?

Metildigoxin may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea - Vomiting - Blurred vision - Fatigue

Serious or Rare Side Effects: - Cardiac arrhythmias (including ventricular tachycardia) - Severe bradycardia - Hyperkalemia

What precautions apply to Metildigoxin?

Careful assessment and monitoring are required when prescribing Metildigoxin.

- Renal impairment: adjust dose and monitor serum levels. - Electrolyte disturbances: correct potassium and magnesium before initiation. - Thyroid disease: use with caution in hyperthyroidism. - Pregnancy: safety not established; avoid unless essential. - Concomitant cardiac glycosides: avoid combined use. - Store at ambient temperature: keep in the original container, protect from moisture.

What does Metildigoxin interact with?

Metildigoxin interacts with several medicines that can modify its safety or efficacy.

Major Interactions (Avoid): - Amiodarone - Quinidine - Verapamil

Moderate Interactions (Monitor Closely): - Diuretics (especially thiazides) - ACE inhibitors - NSAIDs

Frequently asked questions

What conditions is Lanitop used to treat?+
Lanitop contains Metildigoxin, which is prescribed for the chronic management of symptomatic heart failure and for rate control in atrial fibrillation, particularly when a rapid ventricular response is present.
How does Metildigoxin work in the body?+
Metildigoxin inhibits the Na⁺/K⁺‑ATPase pump on cardiac cells, leading to increased intracellular sodium and calcium. The rise in calcium improves myocardial contractility and slows atrioventricular nodal conduction, helping both heart failure and atrial fibrillation.
What is the usual dose of Lanitop?+
The dosage of Lanitop is individualized by the prescribing clinician based on the patient’s clinical status, renal function, electrolyte balance and response to therapy. No fixed regimen is provided here.
Is Lanitop safe during pregnancy or breastfeeding?+
Safety data for Metildigoxin in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and decisions are made by the treating physician.
How do I order Lanitop from GNH USA?+
To place an order, submit an enquiry on the Lanitop product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Lanitop compare with other cardiac glycosides?+
Metildigoxin belongs to the same class as digoxin and digitoxin, sharing a similar mechanism of Na⁺/K⁺‑ATPase inhibition. Differences may exist in potency, half‑life and tissue distribution, which influence dosing frequency and monitoring requirements. Clinical choice depends on individual patient factors and physician judgment.
What are the storage requirements for Lanitop?+
Lanitop should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability.
How is Lanitop administered?+
Lanitop is taken orally, usually as a tablet, and should be swallowed with water. The exact timing and relation to meals are determined by the prescribing clinician to optimise absorption and therapeutic effect.
What are the most serious risks associated with Lanitop?+
The most serious risks include life‑threatening cardiac arrhythmias, severe bradycardia, heart block and marked hyperkalemia. Patients should be monitored closely for any signs of these events, especially during dose initiation or adjustment.
Who should not use Lanitop?+
Lanitop is contraindicated in patients with known hypersensitivity to Metildigoxin or other cardiac glycosides, those with uncontrolled ventricular arrhythmias, severe electrolyte disturbances (especially hyper‑kalemia), and in individuals where the risk outweighs the therapeutic benefit as judged by a qualified clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metildigoxin
Route
Oral Use
Manufacturer
Esteve Pharmaceuticals Gmbh
Origin
EU

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