Lamotrigin Teva

Lamotrigine, the active ingredient in Lamotrigin Teva, is an anticonvulsant presented as an oral tablet for oral use. It is used to treat various seizure types and as maintenance therapy for bipolar disorder in adults.\n\nGNH India supplies Lamotrigin Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lamotrigine is an anticonvulsant that acts on neuronal excitability in seizure disorders and mood stabilization in bipolar disorder.\n\nEpilepsy (partial seizures): reduces the frequency and severity of focal seizures.\nGeneralized seizures: helps control tonic‑clonic and absence seizures.\nBipolar disorder (maintenance therapy): maintains mood stability and lowers the risk of depressive relapse.

Lamotrigine may cause a range of adverse reactions, from mild to severe.\n\nCommon Side Effects:\n- Dizziness\n- Headache\n- Nausea or vomiting\n- Rash (mild)\n- Blurred vision\n- Fatigue\n\nSerious or Rare Side Effects:\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis\n- Severe skin reactions (e.g., bullous pemphigoid)\n- Blood dyscrasias such as agranulocytosis\n- Hepatic failure\n- Suicidal thoughts or behavior\n- Aseptic meningitis

Before initiating lamotrigine therapy, consider the following precautions.\n\nPregnancy: consult a physician; safety data are limited.\nRenal impairment: dose may require adjustment and monitoring.\nHepatic impairment: monitor liver function tests regularly.\nConcomitant valproic acid: increased risk of severe skin reactions; monitor closely.\nDo not discontinue abruptly: sudden withdrawal may precipitate seizures.\nStore at room temperature: keep in the original container, protect from moisture and light.

Lamotrigine interacts with several medicines that can alter its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Valproic acid: markedly increases lamotrigine levels and risk of skin reactions.\n- Carbamazepine: reduces lamotrigine concentrations, potentially decreasing efficacy.\n- Phenobarbital: lowers lamotrigine levels, requiring dose adjustment.\n\nModerate Interactions (Monitor Closely):\n- Oral contraceptives: may increase lamotrigine clearance, reducing therapeutic effect.\n- Serotonergic agents (e.g., SSRIs, MAOIs): monitor for signs of serotonin syndrome.