GNH USA

Europe — EMA

Lamivudine Viatris

GNH USA supplies Lamivudine Viatris (Lamivudine), a nucleoside reverse transcriptase inhibitor for HIV infection and chronic hepatitis B. Request a quote.

Lamivudine

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What is Lamivudine?

Lamivudine, the active ingredient in Lamivudine Viatris, is a nucleoside reverse transcriptase inhibitor presented as an oral dosage form for oral use. It is employed in the management of Human Immunodeficiency Virus (HIV) infection and chronic hepatitis B in adult patients.

GNH USA supplies Lamivudine Viatris as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, transplant centres and clinics worldwide with rigorous quality assurance and regulatory adherence. The company manages global logistics, ensuring timely delivery and compliance with import requirements.

What is Lamivudine used for?

Lamivudine acts on viral replication pathways and is indicated for the following conditions:

- HIV infection: reduces viral load and helps restore immune function. - Chronic hepatitis B infection: suppresses HBV DNA replication and improves liver enzyme profiles. - HIV/HBV co‑infection: provides combined antiviral activity against both viruses.

What are the side effects of Lamivudine?

Lamivudine may cause adverse reactions. Common Side Effects: - Nausea - Headache - Fatigue - Diarrhea

Serious or Rare Side Effects: - Lactic acidosis - Severe hepatotoxicity - Hypersensitivity reactions (including rash or Stevens‑Johnson syndrome)

What precautions apply to Lamivudine?

When prescribing Lamivudine, consider the following precautions: - Monitor renal function: adjust dose in renal impairment. - Assess hepatic function: watch for signs of liver toxicity. - Evaluate risk of lactic acidosis: especially in patients with mitochondrial disorders. - Use caution in pregnancy: weigh benefits against potential risks. - Review concomitant medications: avoid known major interactions. - Store at room temperature: keep in the original container, protect from moisture.

What does Lamivudine interact with?

Lamivudine can interact with several agents. Major Interactions (Avoid): - Didanosine: increased risk of peripheral neuropathy. - Stavudine: heightened mitochondrial toxicity. - Tenofovir: potential additive renal toxicity. - Ribavirin: may augment hepatotoxic effects.

Moderate Interactions (Monitor Closely): - Efavirenz: possible reduction in lamivudine plasma levels. - Nevirapine: enzyme induction may alter lamivudine exposure. - Alcohol: can exacerbate liver injury.

Frequently asked questions

What is Lamivudine Viatris used for?+
Lamivudine Viatris is used as an antiretroviral medication to treat Human Immunodeficiency Virus (HIV) infection and as an antiviral agent for chronic hepatitis B infection. It helps lower viral load, improve immune function in HIV patients, and suppress hepatitis B virus replication in the liver.
How does lamivudine work?+
Lamivudine is a nucleoside analogue that is converted inside cells to its active triphosphate form. This active metabolite competes with natural nucleotides for incorporation into viral DNA by reverse transcriptase, causing premature chain termination and preventing the virus from replicating its genetic material.
What is the usual dose of lamivudine?+
The dosage of lamivudine is individualized by the prescribing healthcare professional based on the patient’s condition, weight, renal function and other clinical factors. Patients should follow the dose and schedule provided by their prescriber and not adjust the amount without medical advice.
Is lamivudine safe in pregnancy or breastfeeding?+
Lamivudine may be used during pregnancy when the potential benefits outweigh any possible risks to the fetus, as determined by a qualified clinician. Limited data are available for breastfeeding, and a healthcare provider should assess the risk‑benefit profile before continuing therapy while nursing.
How do I order Lamivudine Viatris from GNH USA?+
To order Lamivudine Viatris, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does lamivudine compare with other antiretroviral drugs?+
Lamivudine belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class and is often combined with other antiretrovirals for synergistic effect. Compared with older NRTIs such as zidovudine, lamivudine generally has a more favorable tolerability profile and a lower incidence of mitochondrial toxicity, though drug‑specific interactions must still be considered.
How should Lamivudine Viatris be stored and handled?+
Lamivudine Viatris should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.
How is Lamivudine Viatris administered?+
Lamivudine Viatris is taken orally, usually as a tablet, with or without food as directed by a healthcare professional. The exact administration schedule, including timing and whether it is taken once or twice daily, is determined by the prescriber based on the individual treatment plan.
What are the most serious risks associated with lamivudine?+
Serious risks include lactic acidosis, severe hepatotoxicity, and hypersensitivity reactions such as rash or Stevens‑Johnson syndrome. Patients should be educated to seek immediate medical attention if they experience unexplained fatigue, abdominal pain, rapid breathing, jaundice, or severe skin reactions.
Who should not use lamivudine?+
Lamivudine is contraindicated in patients with known hypersensitivity to the drug or any of its components. Caution is also advised for individuals with pre‑existing severe liver disease, mitochondrial disorders, or those receiving contraindicated medications such as didanosine or stavudine.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lamivudine
Route
Oral Use
Manufacturer
Viatris Sante
Origin
EU

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