GNH USA

Europe — EMA

Lamivudine Teva Pharma

GNH USA supplies Lamivudine Teva Pharma (Lamivudine), a nucleoside reverse transcriptase inhibitor for HIV-1 infection and chronic hepatitis B.

Lamivudine

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What is Lamivudine?

Lamivudine, the active ingredient in Lamivudine Teva Pharma, is a nucleoside reverse transcriptase inhibitor presented as a tablet for oral use. It treats HIV-1 infection and chronic hepatitis B infection in adults and children as prescribed.

GNH USA supplies Lamivudine Teva Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Lamivudine used for?

Lamivudine is used in antiretroviral therapy and antiviral treatment of hepatitis B, acting on viral replication pathways. - HIV-1 infection: suppresses viral replication and helps restore immune function. - Chronic hepatitis B infection: reduces viral load and slows disease progression. - Prevention of mother‑to‑child transmission of HIV: lowers the risk of vertical transmission when used in combination regimens.

What are the side effects of Lamivudine?

Lamivudine is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea - Headache - Fatigue - Diarrhea - Insomnia - Dizziness

Serious or Rare Side Effects: - Lactic acidosis - Severe hepatotoxicity - Pancreatitis - Severe skin reactions (e.g., Stevens‑Johnson syndrome) - Bone marrow suppression - Hypersensitivity reactions

What precautions apply to Lamivudine?

Lamivudine requires careful monitoring in several clinical situations. - Renal impairment: assess renal function and adjust dose if necessary. - Hepatic impairment: monitor liver enzymes regularly. - Pregnancy: category B; discuss risks and benefits with a healthcare provider. - Lactation: evaluate infant exposure and consider alternatives. - Concomitant antiretroviral therapy: monitor for additive toxicities. - Store at below 25°C: keep in the original pack, protect from moisture.

What does Lamivudine interact with?

Lamivudine may interact with other antiviral and systemic agents.

Major Interactions (Avoid): - Didanosine: increased risk of pancreatitis. - Stavudine: heightened mitochondrial toxicity. - Zidovudine: additive bone‑marrow suppression.

Moderate Interactions (Monitor Closely): - Protease inhibitors: may raise lamivudine plasma levels. - Non‑nucleoside reverse transcriptase inhibitors: can affect antiviral efficacy. - Nephrotoxic drugs: require renal function monitoring.

Frequently asked questions

What conditions is Lamivudine Teva Pharma used to treat?+
Lamivudine Teva Pharma is indicated for the treatment of HIV‑1 infection and chronic hepatitis B infection. It is also used as part of combination therapy to reduce the risk of mother‑to‑child transmission of HIV during pregnancy.
How does lamivudine work in the body?+
Lamivudine is a nucleoside analog that is converted inside cells to its active triphosphate form. This active metabolite competes with natural nucleosides for incorporation into viral DNA by reverse transcriptase, causing premature chain termination and halting viral replication.
What is the usual dose of lamivudine?+
The prescribed dose of lamivudine is determined by the treating physician based on the patient’s age, weight, renal function, and the specific indication. Dosage regimens may differ for HIV versus hepatitis B treatment.
Is lamivudine safe to use during pregnancy or breastfeeding?+
Lamivudine is classified as pregnancy category B, indicating that animal studies have not shown risk to the fetus and there are no well‑controlled studies in pregnant women. It may be used during pregnancy when the potential benefit justifies the potential risk. Breastfeeding decisions should be made in consultation with a healthcare professional.
How do I order Lamivudine Teva Pharma from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does lamivudine compare with other antiretroviral drugs?+
Lamivudine belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class, offering a favorable safety profile and convenient once‑daily dosing. Compared with older NRTIs such as didanosine or stavudine, lamivudine has lower rates of mitochondrial toxicity and peripheral neuropathy, making it a common component of modern combination regimens.
What are the recommended storage conditions for lamivudine tablets?+
Lamivudine tablets should be stored at temperatures below 25 °C, in their original packaging, and protected from moisture and direct sunlight. Do not store in a humid environment or expose to excessive heat.
How is lamivudine administered to patients?+
Lamivudine is taken orally, usually with or without food, as a whole tablet. The exact timing and whether it should be taken with meals are determined by the prescribing clinician.
What are the most serious risks associated with lamivudine therapy?+
Serious risks include lactic acidosis, severe hepatotoxicity, pancreatitis, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome. Patients should be educated to report unexplained abdominal pain, rapid weight loss, persistent nausea, or skin rashes promptly.
Who should not use lamivudine?+
Lamivudine is contraindicated in patients with known hypersensitivity to the drug or any of its components. Caution is also advised for individuals with severe renal or hepatic impairment, and it should be avoided in combination with drugs that have overlapping toxicities unless closely monitored.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lamivudine
Route
Oral Use
Manufacturer
Teva B.V
Origin
EU

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