Lamivudine Teva

Lamivudine, the active ingredient in Lamivudine Teva, is a nucleoside reverse transcriptase inhibitor presented as an oral tablet for oral use. It is used to treat human immunodeficiency virus (HIV) infection and chronic hepatitis B infection in adults and children as prescribed by a qualified health professional.

GNH USA supplies Lamivudine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lamivudine is an antiretroviral and antiviral agent that targets viral replication in HIV and hepatitis B virus infections.

HIV infection: reduces plasma viral load and helps restore immune function. Chronic hepatitis B infection: suppresses HBV DNA synthesis, decreasing liver inflammation and disease progression. HIV‑2 infection: inhibits viral replication, contributing to disease control when used in combination therapy.

Lamivudine may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: transient stomach upset. - Headache: mild to moderate intensity. - Fatigue: general tiredness. - Diarrhea: loose stools.

Serious or Rare Side Effects: - Lactic acidosis: buildup of lactate, potentially life‑threatening. - Severe hepatotoxicity: marked liver enzyme elevation. - Pancreatitis: inflammation of the pancreas. - Stevens‑Johnson syndrome: severe skin reaction. - Bone‑marrow suppression: reduced blood cell production. - Hypersensitivity reactions: rash, fever, eosinophilia.

Lamivudine requires careful monitoring and patient education to minimize risks.

Monitor liver function: perform baseline and periodic liver enzyme tests. Assess renal function: adjust dosing in patients with impaired kidney function. Check hepatitis B status: identify co‑infection before initiating therapy. Avoid in known hypersensitivity: discontinue if allergic reaction occurs. Use with caution in pregnancy: weigh benefits against potential risks. Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Lamivudine can interact with several antiretroviral and non‑antiretroviral agents.

Major Interactions (Avoid): - Didanosine: increased risk of pancreatitis and mitochondrial toxicity. - Stavudine: heightened mitochondrial toxicity and peripheral neuropathy. - Ribavirin: enhanced hematologic toxicity.

Moderate Interactions (Monitor Closely): - Tenofovir: monitor renal function and phosphate levels. - Efavirenz: watch for central nervous system effects. - Alcohol: may exacerbate liver enzyme elevations.