GNH USA

Europe — EMA

Lamivudin Aurobindo

GNH USA supplies Lamivudin Aurobindo (Lamivudine), a nucleoside reverse transcriptase inhibitor for HIV infection and chronic hepatitis B.

Lamivudine

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What is Lamivudine?

Lamivudine, the active ingredient in Lamivudin Aurobindo, is a nucleoside reverse transcriptase inhibitor (NRTI) presented as an oral tablet for oral use. It treats HIV infection and chronic hepatitis B in adults and children as prescribed.

GNH USA supplies Lamivudin Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Lamivudine used for?

Lamivudin Aurobindo is used in the management of viral infections that target the reverse transcriptase pathway.

- HIV infection: reduces viral load and helps restore immune function. - Chronic hepatitis B: suppresses viral replication and improves liver enzyme levels. - HIV/HBV co‑infection: provides simultaneous control of both viruses in patients with dual infection.

What are the side effects of Lamivudine?

Lamivudin Aurobindo may cause a range of adverse reactions. Most are mild and reversible, but serious events can occur.

Common Side Effects: - Nausea - Headache - Fatigue - Diarrhea - Insomnia - Abdominal pain

Serious or Rare Side Effects: - Lactic acidosis - Severe hepatotoxicity - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Pancreatitis - Severe hypersensitivity reactions - Grade 3–4 neutropenia or anemia

What precautions apply to Lamivudine?

Lamivudin Aurobindo requires careful monitoring and patient counseling to minimise risks. - Liver function monitoring: assess baseline enzymes and repeat periodically. - Renal function assessment: adjust dose in severe impairment. - HBV reactivation watch: monitor hepatitis B surface antigen in patients discontinuing therapy. - Adherence counseling: emphasize the importance of consistent dosing to prevent resistance. - Hypersensitivity avoidance: discontinue if severe rash or anaphylaxis occurs. - Store at below 25°C: keep in the original pack, protect from moisture.

What does Lamivudine interact with?

Lamivudin Aurobindo can interact with several antiretroviral and non‑antiretroviral agents.

Major Interactions (Avoid): - Didanosine: increased risk of pancreatitis. - Stavudine: heightened mitochondrial toxicity. - Ribavirin: enhanced hematologic toxicity.

Moderate Interactions (Monitor Closely): - Efavirenz: possible reduction in lamivudine plasma levels. - Nevirapine: potential liver enzyme elevation. - Alcohol: may exacerbate hepatic adverse effects.

Frequently asked questions

What is Lamivudin Aurobindo used for?+
Lamivudin Aurobindo contains lamivudine, an antiretroviral drug indicated for the treatment of HIV infection and chronic hepatitis B. It is prescribed to reduce viral load, improve immune function in HIV, and suppress hepatitis B virus replication in infected patients.
How does lamivudine work?+
Lamivudine is a nucleoside analogue that mimics natural nucleotides. It is incorporated into viral DNA by reverse transcriptase, lacking a 3'-hydroxyl group, which halts DNA chain elongation and prevents the virus from replicating its genome.
What is the usual dose of lamivudine?+
The specific dose of Lamivudin Aurobindo is determined by the prescribing clinician based on the patient’s condition, weight, renal function, and treatment guidelines. Only a qualified healthcare professional should set the dosing regimen.
Is lamivudine safe during pregnancy or breastfeeding?+
Safety data for lamivudine in pregnancy are limited, and the medication should only be used if the potential benefit justifies any potential risk to the fetus. Breastfeeding decisions should be made with a healthcare provider, as lamivudine can be excreted in breast milk.
How do I order Lamivudin Aurobindo from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does lamivudine compare with other antiretroviral drugs?+
Lamivudine is a nucleoside reverse transcriptase inhibitor, often used in combination regimens. Compared with other NRTIs, it has a favorable safety profile and low pill burden, but resistance can develop if used as monotherapy. Clinicians typically combine it with drugs from other classes for optimal viral suppression.
What are the storage and handling requirements for Lamivudin Aurobindo?+
Lamivudin Aurobindo tablets should be stored at temperatures below 25 °C, in the original container, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date printed on the packaging.
How is Lamivudin Aurobindo administered?+
The medication is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water. Patients should follow the dosing schedule precisely to maintain effective drug levels.
What are the most serious risks associated with lamivudine?+
Serious adverse events include lactic acidosis, severe hepatotoxicity, Stevens‑Johnson syndrome, and pancreatitis. Patients should be monitored for unexplained fatigue, abdominal pain, jaundice, rash, or signs of pancreatic inflammation, and seek immediate medical attention if these occur.
Who should not use Lamivudin Aurobindo?+
Lamivudin Aurobindo should be avoided in individuals with known hypersensitivity to lamivudine or any of the tablet excipients. Caution is also advised for patients with severe hepatic or renal impairment, and it is not recommended for use in patients with active, severe mitochondrial disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lamivudine
Route
Oral Use
Manufacturer
Puren Pharma Gmbh & Co. Kg
Origin
EU

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