GNH USA

Europe — EMA

Lamisilatt

GNH USA supplies Lamisilatt (Terbinafine Hydrochloride), a allylamine antifungal for athlete's foot, ringworm and jock itch.

Terbinafine Hydrochloride

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What is Terbinafine Hydrochloride?

Terbinafine Hydrochloride, the active ingredient in Lamisilatt, is an allylamine antifungal presented as a topical formulation for cutaneous use. It treats superficial dermatophyte infections such as athlete’s foot, ringworm and jock itch in adults and children when applied to the affected skin, and is indicated for use on intact skin of the feet, body and groin areas.

GNH USA supplies Lamisilatt as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and export regulations.

What is Terbinafine Hydrochloride used for?

Terbinafine Hydrochloride is an allylamine antifungal that targets dermatophyte infections of the skin. - Tinea pedis (athlete’s foot): Reduces fungal growth and alleviates itching, scaling and redness on the feet. - Tinea corporis (ringworm): Clears skin lesions and prevents spread of infection on the body. - Tinea cruris (jock itch): Relieves irritation and eliminates fungal colonies in the groin area. - Other superficial fungal skin infections: Improves symptoms of cutaneous candidiasis and similar conditions.

What are the side effects of Terbinafine Hydrochloride?

Topical terbinafine may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity. Common Side Effects: - Itching or pruritus - Burning sensation at the application site - Redness or erythema Serious or Rare Side Effects: - Severe allergic reaction (angioedema or anaphylaxis) - Contact dermatitis with blistering - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Persistent swelling or ulceration of the skin

What precautions apply to Terbinafine Hydrochloride?

When using Lamisilatt, follow these safety measures: - Avoid application on broken or inflamed skin: Do not apply to open wounds or irritated areas. - Do not use if you have known hypersensitivity to terbinafine or other allylamines: discontinue immediately if a reaction occurs. - Limit treatment to the prescribed area and duration: excessive use may increase irritation. - Monitor for worsening symptoms: seek medical advice if infection does not improve within two weeks. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Terbinafine Hydrochloride interact with?

Terbinafine topical has limited systemic interactions, but consider the following: Major Interactions (Avoid): - Concurrent use of systemic terbinafine or other oral antifungals: may increase systemic exposure and risk of adverse reactions. - Co‑application with other topical antifungal agents containing azoles: can cause increased skin irritation.

Moderate Interactions (Monitor Closely): - Use with CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) if systemic absorption occurs: monitor for systemic side effects. - Concurrent use of corticosteroid creams: may mask signs of infection, requiring close observation. - Application with occlusive dressings: may enhance absorption and increase risk of irritation.

Frequently asked questions

What conditions is Lamisilatt used to treat?+
Lamisilatt is indicated for the topical treatment of superficial dermatophyte infections such as tinea pedis (athlete’s foot), tinea corporis (ringworm), tinea cruris (jock itch) and other similar superficial fungal skin infections.
How does terbinafine work to treat fungal infections?+
Terbinafine inhibits the fungal enzyme squalene epoxidase, preventing the conversion of squalene to ergosterol. This causes toxic squalene to accumulate and depletes ergosterol, a vital component of the fungal cell membrane, leading to loss of membrane integrity and fungal cell death.
What is the usual dose of Lamisilatt?+
The prescribed dose of Lamisilatt is determined by a healthcare professional. Typically, a thin layer is applied to the affected skin once daily for a period defined by the prescriber, based on the severity and location of the infection.
Is Lamisilatt safe to use during pregnancy or while breastfeeding?+
Safety data for topical terbinafine in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.
How do I order Lamisilatt from GNH USA?+
To place an order, submit an enquiry on the Lamisilatt product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Lamisilatt compare with other antifungal classes?+
Lamisilatt (terbinafine) belongs to the allylamine class, which inhibits squalene epoxidase, whereas azole antifungals block lanosterol 14‑α‑demethylase. Allylamines often achieve faster fungicidal activity against dermatophytes and have a different safety profile, making them a useful alternative when azoles are ineffective or not tolerated.
How should Lamisilatt be stored?+
Store Lamisilatt at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.
How is Lamisilatt applied?+
Clean and dry the affected skin area before use. Apply a thin, even layer of Lamisilatt to the lesion and a small margin of surrounding skin, once daily or as directed by the prescriber. Wash hands after application and avoid covering the treated area with occlusive dressings unless instructed.
What are the most serious risks associated with Lamisilatt?+
Serious adverse reactions, although rare, include severe allergic responses such as angioedema or anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and extensive contact dermatitis with blistering. Immediate medical attention is required if any of these symptoms develop.
Who should not use Lamisilatt?+
Individuals with a known hypersensitivity to terbinafine, other allylamines, or any component of the formulation should avoid using Lamisilatt. It should also not be applied to broken, inflamed or infected skin without medical advice.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine Hydrochloride
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

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