Lamisil Uno

Terbinafine, the active ingredient in Lamisil Uno, is an allylamine antifungal presented as a topical formulation for topical use. It treats superficial dermatophyte infections such as athlete's foot, ringworm and jock itch in adults and children.

GNH USA supplies Lamisil Uno as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Terbinafine is indicated for the treatment of superficial fungal infections caused by dermatophytes.

- Tinea pedis (athlete's foot): reduces itching and clears the infection on the feet. - Tinea corporis (ringworm): eliminates the rash and prevents spread on the body. - Tinea cruris (jock itch): relieves irritation and eradicates the fungus in the groin area.

Terbinafine is generally well tolerated when applied to the skin, but some adverse reactions may occur.

Common Side Effects: - Local itching or burning at the application site. - Redness or mild rash. - Dryness or peeling of the skin. - Stinging sensation. - Minor swelling. - Slight irritation.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., swelling of face, lips, tongue). - Contact dermatitis with blistering. - Widespread rash or hives. - Significant skin discoloration. - Systemic symptoms such as fever or malaise. - Unexplained liver enzyme elevation (rare).

Before using Lamisil Uno, consider the following safety measures.

- Allergy Check: avoid if you have known hypersensitivity to terbinafine or formulation excipients. - Skin Integrity: do not apply to broken, inflamed, or infected skin beyond the fungal infection. - Age Consideration: use in children only under medical supervision. - Concomitant Medications: inform your clinician of any systemic antifungal or liver‑affecting drugs. - Pregnancy & Breastfeeding: discuss risks with a healthcare professional before use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Terbinafine may interact with other medicines, especially when systemic absorption occurs.

Major Interactions (Avoid): - Oral antifungal agents (e.g., itraconazole, fluconazole) that share metabolic pathways. - Drugs highly dependent on CYP2D6 metabolism, as terbinafine can inhibit this enzyme.

Moderate Interactions (Monitor Closely): - Hepatotoxic medications (e.g., acetaminophen high doses) requiring liver function monitoring. - Warfarin, where altered metabolism may affect coagulation parameters. - Topical corticosteroids applied to the same area, which may increase systemic absorption.