GNH USA

Europe — EMA

Lamisil

GNH USA supplies Lamisil (Terbinafine), an allylamine antifungal for tinea pedis, tinea corporis, tinea cruris and topical onychomycosis.

Terbinafine Hydrochloride

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What is Terbinafine Hydrochloride?

Terbinafine, the active ingredient in Lamisil, is an allylamine antifungal presented as a topical formulation for skin use. It treats fungal infections of the skin and nails in adults and children as directed by a healthcare professional.

GNH USA supplies Lamisil as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Terbinafine Hydrochloride used for?

Lamisil is an allylamine antifungal indicated for superficial fungal infections of the skin and nails.

- Tinea pedis: reduces fungal growth and relieves itching, scaling and redness on the feet. - Tinea corporis: clears ring‑shaped lesions by inhibiting the causative dermatophytes. - Tinea cruris: alleviates itching and erythema in the groin area. - Onychomycosis (topical treatment): improves nail appearance by limiting fungal colonisation on the nail surface.

What are the side effects of Terbinafine Hydrochloride?

Common Side Effects: - Itching at the application site - Burning sensation - Redness or erythema - Dryness or peeling of skin - Stinging feeling - Mild rash

Serious or Rare Side Effects: - Severe contact dermatitis - Allergic reactions such as swelling or hives - Stevens‑Johnson syndrome (very rare) - Photosensitivity reactions - Significant liver enzyme elevation (systemic absorption) - Persistent ulceration or infection at the site of application

What precautions apply to Terbinafine Hydrochloride?

Before using Lamisil, consider the following precautions: - Avoid use on broken or inflamed skin: apply only to intact epidermis. - Do not apply to mucous membranes: keep away from eyes, mouth and genital mucosa. - Limit exposure to sunlight: use sunscreen if treated area will be exposed. - Discontinue if severe irritation occurs: seek medical advice promptly. - Consult a physician if infection persists beyond the recommended treatment period. - Store at room temperature: keep in the original container, protect from moisture and heat.

What does Terbinafine Hydrochloride interact with?

Terbinafine topical may interact with other agents applied to the skin.

Major Interactions (Avoid): - Concurrent oral terbinafine: increased risk of systemic toxicity. - Topical corticosteroids: may reduce antifungal efficacy. - Other topical antifungals: can cause excessive irritation.

Moderate Interactions (Monitor Closely): - Alcohol‑based hand sanitizers: may increase skin dryness. - Skin care products containing acids (e.g., glycolic acid): monitor for irritation. - Phototoxic agents (e.g., psoralen): watch for enhanced photosensitivity.

Frequently asked questions

What conditions is Lamisil used to treat?+
Lamisil is indicated for the topical treatment of superficial fungal infections such as athlete's foot (tinea pedis), ringworm of the body (tinea corporis), jock itch (tinea cruris), and mild cases of nail fungus (topical onychomycosis). It works by targeting the fungi that cause these skin and nail conditions.
How does terbinafine, the active ingredient in Lamisil, work?+
Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, an essential component of fungal cell membranes. The resulting buildup of squalene and loss of ergosterol compromise the fungal cell structure, leading to cell death while sparing human cells.
What is the usual dose of Lamisil?+
The specific dose and frequency of Lamisil are determined by the prescribing healthcare professional based on the infection type, severity, patient age, and treatment guidelines. Patients should follow the prescriber’s instructions and the product label for optimal results.
Is Lamisil safe to use during pregnancy or breastfeeding?+
Safety data for topical terbinafine during pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil.
How do I order Lamisil from GNH USA?+
To place an order, submit an enquiry on the Lamisil product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lamisil compare with other antifungal treatments?+
Lamisil belongs to the allylamine class, which acts on a different fungal pathway than azole antifungals (e.g., clotrimazole). Allylamines often achieve faster fungal clearance and are effective against dermatophytes resistant to some azoles, making Lamisil a valuable alternative for certain skin infections.
How should Lamisil be stored and handled?+
Store Lamisil at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat. Ensure the container is tightly closed when not in use to maintain stability.
How is Lamisil applied?+
Apply a thin layer of the cream or gel to the affected skin area once or twice daily, as directed by the prescriber. Gently rub it in until fully absorbed, and wash hands before and after application to avoid accidental contact with eyes or mucous membranes.
What are the most serious risks associated with Lamisil?+
While uncommon, serious adverse reactions can include severe contact dermatitis, allergic swelling or hives, Stevens‑Johnson syndrome, and systemic effects such as liver enzyme elevation if significant absorption occurs. Patients should stop use and seek medical attention if they notice any severe or unexpected symptoms.
Who should not use Lamisil?+
Lamisil should not be used on broken, inflamed or infected skin, on mucous membranes, or by individuals with a known hypersensitivity to terbinafine or any component of the formulation. Patients with severe liver disease should also avoid use unless specifically advised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine Hydrochloride
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

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